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Geoffrey S. Young, MD
Associate Radiologist, Brigham and Women's Hospital
Assistant Professor of Radiology, Harvard Medical School

Brigham and Women's Hospital
Department of Radiology
75 Francis Street
Boston, MA 02115


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Research Narrative:

Geoffrey Young’s research focuses on advanced MRI, CT and optical imaging of CNS diseases for diagnosis, surgical and radiotherapeutic decision making and guidance, and therapeutic follow-up. He has a special interest in brain tumors, epilepsy, image guidance of neurosurgery, and improvement of quality and safety in Neuroradiology including MRI safety and CT radiation safety. Ongiong original research areas include machine learning and other techniques for computer assisted diagnosis of brain tumor, epilepsy and vascular abnormalities, MRI and optical molecular and physiologic imaging techniques for assessing brain tumor bloodflow, invasion, cellularity, oxygenation (DSC PWI, DWI, DTI, BOLD, ASL and volumetrics), dynamic 4-D whole brain CT angiography and perfusion for assessment of neurovascular disease, and radiation biology


Courses Taught:
2010 - ongoing, BWH, MRI Safety, MRI Safety Instuction for Level 2 MRI Physicians, Researchers and Technologists

Publications (Pulled from Harvard Catalyst Profiles):

1. Nawfel RD, Young GS. Measured Head CT/CTA Skin Dose and Intensive Care Unit Patient Cumulative Exposure. AJNR Am J Neuroradiol. 2017 Mar; 38(3):455-461.

2. Qin L, Li X, Stroiney A, Qu J, Helgager J, Reardon DA, Young GS. Advanced MRI assessment to predict benefit of anti-programmed cell death 1 protein immunotherapy response in patients with recurrent glioblastoma. Neuroradiology. 2017 Feb; 59(2):135-145.

3. Qu JR, Young GS. Handbook of Neuro-Oncology Neuroimaging, Newton HB ed. Advanced MR Imaging of Brain Tumor. 2016; 167-81.

4. Qu J, Qin L, Cheng S, Leung K, Li X, Li H, Dai J, Jiang T, Akgoz A, Seethamraju R, Wang Q, Rahman R, Li S, Ai L, Jiang T, Young GS. Residual low ADC and high FA at the resection margin correlate with poor chemoradiation response and overall survival in high-grade glioma patients. Eur J Radiol. 2016 Mar; 85(3):657-64.

5. Abd-El-Barr MM, Santos SM, Aglio LS, Young GS, Mukundan S, Golby AJ, Gormley WB, Dunn IF. "Extraoperative" MRI (eoMRI) for Brain Tumor Surgery: Initial Results at a Single Institution. World Neurosurg. 2015 Jun; 83(6):921-8.

6. Himes N, Young GS. Image-Guided Neurosurgery, Golby AJ ed. Background on Imaging, Structural Imaging. 2015; 23-61.

7. Akgoz A, Rahman R, You H, Qu J, Hamdan A, Seethamraju RT, Wen PY, Young GS. Spin-echo echo-planar perfusion prior to chemoradiation is a strong independent predictor of progression-free and overall survival in newly diagnosed glioblastoma. J Neurooncol. 2014 Aug; 119(1):111-9.

8. Saar BG, Freudiger CW, Xu X, Huttner A, Kesari S, Young G, Xie XS. Coherent Raman tissue imaging in the brain. Cold Spring Harb Protoc. 2014 May 01; 2014(5).

9. Ji M, Orringer DA, Freudiger CW, Ramkissoon S, Liu X, Lau D, Golby AJ, Norton I, Hayashi M, Agar NY, Young GS, Spino C, Santagata S, Camelo-Piragua S, Ligon KL, Sagher O, Xie XS. Rapid, label-free detection of brain tumors with stimulated Raman scattering microscopy. Sci Transl Med. 2013 Sep 04; 5(201):201ra119.

10. Hochberg AR, Young GS. Cerebral perfusion imaging. Semin Neurol. 2012 Sep; 32(4):454-65.