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JoAnn Elisabeth Manson, MD. DrPH
Physician, Brigham and Women's Hospital
Michael and Lee Bell Professor of Women's Health, Harvard Medical School

Brigham and Women's Hospital
Department of Medicine
Preventive Medicine
75 Francis Street
Boston, MA 02115

Research Location: 900-930 Commonwealth Avenue

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Research Narrative:

The focus of Dr. Manson’s research has been women's health, randomized clinical trials in cardiovascular disease prevention, and population health/translational research.  She has studied the role of lifestyle factors, diet, micronutrient supplementation, and reproductive and hormonal factors as predictors of chronic disease in women.  Other major interests include the role of vitamin D, omega-3s, and folate in the prevention of CVD, diabetes, and cancer. She has studied extensively the role of moderate-intensity exercise as compared with vigorous exercise in the prevention of heart disease, stroke, type 2 diabetes, and breast cancer in women.  She has also been actively involved in studies of biomarker and genetic predictors of cardiovascular disease and diabetes.  She is one of the lead investigators on several landmark women’s health studies, including the Women’s Health Initiative, the Nurses’ Health Study, the Women’s Antioxidant and Folic Acid Cardiovascular Study, and others. 

“Woman in Science” Award from the American Medical Women’s Association in 2003, election to membership in the Association of American Physicians in 2005, the Harvard College Women’s Professional Achievement Award in 2006, fellowship in the American Association for the Advancement of Science (AAAS) in 2007, the American Heart Association’s Population Research Prize in 2010 and Distinguished Scientist Award in 2011, election to the Institute of Medicine (IOM) in 2011.

Publications (Pulled from Harvard Catalyst Profiles):

1. Huang T, Wang T, Heianza Y, Zheng Y, Sun D, Kang JH, Pasquale LR, Rimm EB, Manson JE, Hu FB, Qi L. Habitual consumption of long-chain n-3 PUFAs and fish attenuates genetically associated long-term weight gain. Am J Clin Nutr. 2019 Mar 01; 109(3):665-673.

2. Zhang X, Tu W, Manson JE, Tinker L, Liu S, Cauley JA, Qi L, Mouton C, Martin LW, Hou L, Song Y. Racial/Ethnic Differences in 25-Hydroxy Vitamin D and Parathyroid Hormone Levels and Cardiovascular Disease Risk Among Postmenopausal Women. J Am Heart Assoc. 2019 Feb 19; 8(4):e011021.

3. Driscoll I, Snively BM, Espeland MA, Shumaker SA, Rapp SR, Goveas JS, Casanova RL, Wactawski-Wende J, Manson JE, Rossom R, Brooks J, Hernandez DG, Singleton AB, Resnick SM. A candidate gene study of risk for dementia in older, postmenopausal women: Results from the Women's Health Initiative Memory Study. Int J Geriatr Psychiatry. 2019 Jan 31.

4. Jackson JK, Zong G, MacDonald-Wicks LK, Patterson AJ, Willett WC, Rimm EB, Manson JE, McEvoy MA. Dietary nitrate consumption and risk of coronary heart disease in women from the Nurses' Health Study. Br J Nutr. 2019 Jan 23; 1-19.

5. Luo J, Manson JE, Weitlauf JC, Shadyab AH, Rapp SR, Garcia L, Jonasson JM, Tindle HA, Nassir R, Wactawski-Wende J, Hendryx M. Personality traits and diabetes incidence among postmenopausal women. Menopause. 2019 Jan 21.

6. Reeves KW, Santana MD, Manson JE, Hankinson SE, Zoeller RT, Bigelow C, Sturgeon SR, Spiegelman D, Tinker L, Luo J, Chen B, Meliker J, Bonner MR, Cote ML, Cheng TD, Calafat AM. Urinary Phthalate Biomarker Concentrations and Postmenopausal Breast Cancer Risk. J Natl Cancer Inst. 2019 Jan 10.

7. Bertone-Johnson ER, Manson JE, Purdue-Smithe AC, Hankinson SE, Rosner BA, Whitcomb BW. A prospective study of inflammatory biomarker levels and risk of early menopause. Menopause. 2019 Jan; 26(1):32-38.

8. Luo J, Manson JE, Hendryx M, Shadyab AH, Johnson KC, Dinh PC, Going SB, Chlebowski R, Stefanick ML, Margolis KL. Physical activity and weight gain after smoking cessation in postmenopausal women. Menopause. 2019 Jan; 26(1):16-23.

9. Purdue-Smithe AC, Whitcomb BW, Manson JE, Hankinson SE, Rosner BA, Troy LM, Bertone-Johnson ER. A Prospective Study of Dairy-Food Intake and Early Menopause. Am J Epidemiol. 2019 Jan 01; 188(1):188-196.

10. Chlebowski RT, Mortimer JE, Crandall CJ, Pan K, Manson JE, Nelson R, Johnson KC, Vitolin MZ, Lane D, Wactawski-Wende J, Kwan K, Stefanick ML. Persistent vasomotor symptoms and breast cancer in the Women's Health Initiative. Menopause. 2018 Dec 28.