Stanley W. Ashley, MD - Department of Surgery

Stanley W. Ashley, MD

View Physician Profile

Surgeon, Brigham and Women's Hospital
Frank Sawyer Professor of Surgery, Harvard Medical School
Vice Chairman, Department of Surgery, Brigham and Women's Hospital

Brigham and Women's Hospital
Department of Surgery
General / GI Surgery
75 Francis Street
Boston, MA 02115

Research Location: Thorn Research Building

Research Narrative: Dr. Ashley is focused on practical aspects of measurement of surgical quality and how these can be applied to improve outcomes, particularly for the individual surgeon. Closely related to this, he has an interest in surgical education, both at the graduate and postgraduate (MOC) levels, and its integration into a certification/recertfication process that ensures quality of care. In addition, he continues his clinical and basic science interests in pancreatitis and intestinal pathophysiology.

Education:	Cornell University Medical College, 1981, MD

Other Professional Activities:	Chief Medical Officer, Brigham and Women's Hospital

Publications (Pulled from Harvard Catalyst Profiles): 1. Ashley SW. Foreword. Curr Probl Surg. 2017 Feb; 54(2):37. 2. Yule S, Ashley SW. Sometimes Wrong, Always In Doubt: Is There a Crisis of Confidence in General Surgery Residents? JAMA Surg. 2016 Dec 01; 151(12):1176. 3. Ashley SW. Foreword. Curr Probl Surg. 2016 Dec; 53(12):555. 4. Ashley SW. Foreword. Curr Probl Surg. 2017 Jan; 54(1):5. 5. Sharma G, Wong D, Arnaoutakis DJ, Shah SK, O'Brien A, Ashley SW, Ozaki CK. Systematic identification and management of barriers to vascular surgery patient discharge time of day. J Vasc Surg. 2017 Jan; 65(1):172-178. 6. Ashley SW. Foreword. Curr Probl Surg. 2016 Nov; 53(11):495. 7. Ashley SW. Foreword. Curr Probl Surg. 2016 Oct; 53(10):443. 8. Ashley SW. Foreword. Curr Probl Surg. 2016 Sep; 53(9):401. 9. Ashley SW. Foreword. Curr Probl Surg. 2016 Aug; 53(8):360. 10. Ashley SW. Foreword. Curr Probl Surg. 2016 Jul; 53(7):300. show all 11. Ashley SW. Foreword. Curr Probl Surg. 2016 Jun; 53(6):251. 12. Ashley SW. Foreword. Curr Probl Surg. 2016 May; 53(5):211. 13. Ashley SW. Foreword. Curr Probl Surg. 2016 Apr; 53(4):160. 14. Xourafas D, Ablorh A, Clancy TE, Swanson RS, Ashley SW. Investigating Transitional Care to Decrease Post-pancreatectomy 30-Day Hospital Readmissions for Dehydration or Failure to Thrive. J Gastrointest Surg. 2016 Jun; 20(6):1194-212. 15. Goralnick E, Zinner MJ, Ashley SW. A Death in the Family: Lessons From a Tragedy. Ann Surg. 2016 Feb; 263(2):230-1. 16. Ashley SW. Foreword. Curr Probl Surg. 2016 Mar; 53(3):101. 17. Klingensmith ME, Potts JR, Merrill WH, Eberlein TJ, Rhodes RS, Ashley SW, Valentine RJ, Hunter JG, Stain SC. Surgical Training and the Early Specialization Program: Analysis of a National Program. J Am Coll Surg. 2016 Apr; 222(4):410-6. 18. Mallory MA, Ashley SW. Computed Tomographic Imaging in the Diagnosis of Recurrent Ventral Hernia. JAMA Surg. 2016 Jan; 151(1):13-4. 19. Ashley SW. Foreword. Curr Probl Surg. 2016 Feb; 53(2):54. 20. Ashley SW. Foreword. Curr Probl Surg. 2016 Jan; 53(1):5. 21. Smith AD, de Vos MS, Smink DS, Nguyen LL, Ashley SW. Text paging of surgery residents: Efficacy, work intensity, and quality improvement. Surgery. 2016 Mar; 159(3):930-7. 22. Ashley SW. Foreword. Curr Probl Surg. 2015 Nov; 52(11):443. 23. Ashley SW. Foreword. Curr Probl Surg. 2015 Dec; 52(12):469. 24. Pernar LI, Peyre SE, Hasson RM, Lipsitz S, Corso K, Ashley SW, Breen EM. Exploring the Content of Intraoperative Teaching. J Surg Educ. 2016 Jan-Feb; 73(1):79-84. 25. Patel DN, Wakeam E, Genoff M, Mujawar I, Ashley SW, Diamond LC. Preoperative consent for patients with limited English proficiency. J Surg Res. 2016 Feb; 200(2):514-22. 26. Reardon DP, Atay JK, Ashley SW, Churchill WW, Berliner N, Connors JM. Implementation of a Hemostatic and Antithrombotic Stewardship program. J Thromb Thrombolysis. 2015 Oct; 40(3):379-82. 27. Ashley SW. Foreword. Curr Probl Surg. 2015 Oct; 52(10):403. 28. Ashley SW. Foreword. Curr Probl Surg. 2015 Aug; 52(8):325. 29. Ashley SW. Foreword. Curr Probl Surg. 2015 Sep; 52(9):357. 30. Ashley SW. Foreword. Curr Probl Surg. 2015 Aug; 52(8):325. 31. Ashley SW. Foreword. Curr Probl Surg. 2015 Jul; 52(7):265. 32. Ashley SW. Foreword. Curr Probl Surg. 2015 Jun; 52(6):229. 33. Ashley SW. Foreword. Curr Probl Surg. 2015 May; 52(5):187. 34. Ashley SW. Foreword. Curr Probl Surg. 2015 Apr; 52(4):142. 35. Xourafas D, Tavakkoli A, Clancy TE, Ashley SW. Distal pancreatic resection for neuroendocrine tumors: is laparoscopic really better than open? J Gastrointest Surg. 2015 May; 19(5):831-40. 36. Ashley SW. Foreword. Curr Probl Surg. 2015 Mar; 52(3):82. 37. Ashley SW. Foreword. Curr Probl Surg. 2015 Feb; 52(2):7. 38. Xourafas D, Tavakkoli A, Clancy TE, Ashley SW. Noninvasive intraductal papillary mucinous neoplasms and mucinous cystic neoplasms: recurrence rates and postoperative imaging follow-up. Surgery. 2015 Mar; 157(3):473-83. 39. Ashley SW. Foreword. Curr Probl Surg. 2014 Dec; 51(12):473. 40. Ashley SW. Foreword. Curr Probl Surg. 2015 Jan; 52(1):526. 41. Ashley SW. Foreword. Curr Probl Surg. 2014 Nov; 51(11):437. 42. Wakeam E, Hyder JA, Ashley SW, Weissman JS. Barriers and Strategies for Effective Patient Rescue: A Qualitative Study of Outliers. Jt Comm J Qual Patient Saf. 2014 Nov; 40(11):503-6. 43. Grover G, Tanase A, Elstone A, Ashley S. Chronic venous leg ulcers: Effects of foam sclerotherapy on healing and recurrence. Phlebology. 2016 Feb; 31(1):34-41. 44. Ashley SW. Foreword. Curr Probl Surg. 2014 Oct; 51(10):413. 45. Ashley SW. The management of pancreatic necrosis continues to evolve, and this has been accompanied by significant improvements in outcomes. Foreword. Curr Probl Surg. 2014 Sep; 51(9):369. 46. Bhutta HY, Deelman TE, le Roux CW, Ashley SW, Rhoads DB, Tavakkoli A. Intestinal sweet-sensing pathways and metabolic changes after Roux-en-Y gastric bypass surgery. Am J Physiol Gastrointest Liver Physiol. 2014 Sep 01; 307(5):G588-93. 47. Ashley SW. Foreword. Curr Probl Surg. 2014 Aug; 51(8):337. 48. Wakeam E, Asafu-Adjei D, Ashley SW, Cooper Z, Weissman JS. The association of intensivists with failure-to-rescue rates in outlier hospitals: results of a national survey of intensive care unit organizational characteristics. J Crit Care. 2014 Dec; 29(6):930-5. 49. Dankers CA, Ashley SW. Invited commentary. J Am Coll Surg. 2014 Jun; 218(6):1104. 50. Ashley SW. Foreword. Curr Probl Surg. 2014 Jul; 51(7):297. 51. Ashley SW. Foreword. Curr Probl Surg. 2014 Jun; 51(6):249. 52. Wakeam E, Hevelone ND, Maine R, Swain J, Lipsitz SA, Finlayson SR, Ashley SW, Weissman JS. Failure to rescue in safety-net hospitals: availability of hospital resources and differences in performance. JAMA Surg. 2014 Mar; 149(3):229-35. 53. Ashley SW. Foreword. The need for evidence-based guidelines to direct decisions regarding the appropriateness of our interventions. Curr Probl Surg. 2014 May; 51(5):193. 54. Ashley SW. Pheochromocytomas are rare and usually benign tumors that are increasingly identified as incidental lesions on imaging studies obtained for other reasons. Foreword. Curr Probl Surg. 2014 Apr; 51(4):145. 55. Waseem T, Duxbury M, Ashley SW, Robinson MK. Ghrelin promotes intestinal epithelial cell proliferation through PI3K/Akt pathway and EGFR trans-activation both converging to ERK 1/2 phosphorylation. Peptides. 2014 Feb; 52:113-21. 56. Lee J, Allen R, Ashley S, Becker S, Cummins P, Gbadamosi A, Gooding O, Huston J, Le Couteur J, O'Sullivan D, Wilson S, Lomer MC. British Dietetic Association evidence-based guidelines for the dietary management of Crohn's disease in adults. J Hum Nutr Diet. 2014 Jun; 27(3):207-18. 57. Ashley SW. Foreword. Curr Probl Surg. 2013 Dec; 50(12):553. 58. Ashley SW. Foreword. Curr Probl Surg. 2014 Feb; 51(2):45. 59. Ashley SW. Foreword. Curr Probl Surg. 2013 Nov; 50(11):505. 60. Ashley SW. Foreword. Curr Probl Surg. 2014 Jan; 51(1):5. 61. Ashley SW. Foreword. Curr Probl Surg. 2013 Oct; 50(10):413. 62. Ashley SW. Foreword. Curr Probl Surg. 2013 Sep; 50(9):389. 63. Ashley SW. Foreword. Curr Probl Surg. 2013 Aug; 50(8):345. 64. Bhutta HY, Ashley SW. Demonstrating infection in severe acute pancreatitis: a role for polymerase chain reaction and gene sequencing?*. Crit Care Med. 2013 Aug; 41(8):2048-9. 65. Stain SC, Hiatt JR, Ata A, Ashley SW, Roggin KK, Potts JR, Moore RA, Galante JM, Britt LD, Deveney KE, Ellison EC. Characteristics of highly ranked applicants to general surgery residency programs. JAMA Surg. 2013 May; 148(5):413-7. 66. Keung EZ, Liu X, Nuzhad A, Adams C, Ashley SW, Askari R. Immunocompromised status in patients with necrotizing soft-tissue infection. JAMA Surg. 2013 May; 148(5):419-26. 67. Bhutta HY, Deelman TE, Ashley SW, Rhoads DB, Tavakkoli A. Disrupted circadian rhythmicity of the intestinal glucose transporter SGLT1 in Zucker diabetic fatty rats. Dig Dis Sci. 2013 Jun; 58(6):1537-45. 68. Ashley SW. Foreword. Curr Probl Surg. 2013 Apr; 50(4):141. 69. Keung EZ, Ashley SW. The Appendix: A Culprit for BRCA1 -Associated Intraperitoneal Cancer?Comment on "Risk-Reducing Appendectomy and the Elimination of BRCA1 -Associated Intraperitoneal Cancer". JAMA Surg. 2013 Mar 1; 148(3):291. 70. Ashley SW. Foreward. Curr Probl Surg. 2012 Dec; 49(12):725. 71. Kelz RR, Reinke CE, Cofer JB, Ashley SW, Hebert JC, Ko CY. APDS panel session IV: intersection of surgical outcomes and medical education. J Surg Educ. 2012 Nov-Dec; 69(6):687-92. 72. Ashley SW. Foreword. Curr Probl Surg. 2012 Nov; 49(11):630. 73. Xourafas D, Ardestani A, Ashley SW, Tavakkoli A. Impact of weight-loss surgery and diabetes status on serum ALT levels. Obes Surg. 2012 Oct; 22(10):1540-7. 74. Ashley SW. Foreword. Curr Probl Surg. 2012 Sep; 49(9):521. 75. Bhutta HY, Ashley SW. Hypertension and marginal ulceration after gastric bypass. J Surg Res. 2013 Dec; 185(2):509-10. 76. Ashley SW. Foreword. Curr Probl Surg. 2012 Jul; 49(7):394. 77. Ashley SW. Foreword. Curr Probl Surg. 2012 Jun; 49(6):325. 78. Balakrishnan A, Stearns AT, Ashley SW, Rhoads DB, Tavakkolizadeh A. PER1 modulates SGLT1 transcription in vitro independent of E-box status. Dig Dis Sci. 2012 Jun; 57(6):1525-36. 79. Lengyel BI, Panizales MT, Steinberg J, Ashley SW, Tavakkoli A. Laparoscopic cholecystectomy: What is the price of conversion? Surgery. 2012 Aug; 152(2):173-8. 80. Balakrishnan A, Stearns AT, Park PJ, Dreyfuss JM, Ashley SW, Rhoads DB, Tavakkolizadeh A. Upregulation of proapoptotic microRNA mir-125a after massive small bowel resection in rats. Ann Surg. 2012 Apr; 255(4):747-53. 81. Funk LM, Ashley SW. Minimal invasion and maximal benefit. Arch Surg. 2012 Apr; 147(4):365. 82. Pernar LI, Ashley SW, Smink DS, Zinner MJ, Peyre SE. Master surgeons' operative teaching philosophies: a qualitative analysis of parallels to learning theory. J Surg Educ. 2012 Jul-Aug; 69(4):493-8. 83. Grover S, Ashley SW, Raut CP. Small intestine gastrointestinal stromal tumors. Curr Opin Gastroenterol. 2012 Mar; 28(2):113-23. 84. Khalpey Z, Rajab TK, Ashley SW. Serous cystadenoma causing the double duct sign. J Gastrointest Surg. 2012 Jun; 16(6):1282-3. 85. Hu YY, Peyre SE, Arriaga AF, Osteen RT, Corso KA, Weiser TG, Swanson RS, Ashley SW, Raut CP, Zinner MJ, Gawande AA, Greenberg CC. Postgame analysis: using video-based coaching for continuous professional development. J Am Coll Surg. 2012 Jan; 214(1):115-24. 86. Stearns AT, Balakrishnan A, Radmanesh A, Ashley SW, Rhoads DB, Tavakkolizadeh A. Relative contributions of afferent vagal fibers to resistance to diet-induced obesity. Dig Dis Sci. 2012 May; 57(5):1281-90. 87. Styer KA, Ashley SW, Schmidt I, Zive EM, Eappen S. Implementing the World Health Organization surgical safety checklist: a model for future perioperative initiatives. AORN J. 2011 Dec; 94(6):590-8. 88. O'Brien ME, Myerson JS, Coward JI, Puglisi M, Trani L, Wotherspoon A, Sharma B, Cook G, Ashley S, Gunapala R, Chua S, Popat S. A phase II study of ¹8F-fluorodeoxyglucose PET-CT in non-small cell lung cancer patients receiving erlotinib (Tarceva); objective and symptomatic responses at 6 and 12 weeks. Eur J Cancer. 2012 Jan; 48(1):68-74. 89. Cevasco M, Ashley SW. On our way to improved outcomes after pancreatic surgery. J Surg Res. 2012 May 15; 174(2):e57-8. 90. Ashley SW. Foreword. Curr Probl Surg. 2011 Nov; 48(11):761. 91. Carty MJ, Ashley SW. Too much of a good thing or operating at the fringe. Arch Surg. 2011 Oct; 146(10):1203. 92. Lengyel BI, Azagury D, Varban O, Panizales MT, Steinberg J, Brooks DC, Ashley SW, Tavakkolizadeh A. Laparoscopic cholecystectomy after a quarter century: why do we still convert? Surg Endosc. 2012 Feb; 26(2):508-13. 93. Hanks JB, Ashley SW, Mahvi DM, Meredith WJ, Stain SC, Biester TW, Borman KR. Feast or famine? The variable impact of coexisting fellowships on general surgery resident operative volumes. Ann Surg. 2011 Sep; 254(3):476-83; discussion 483-5. 94. Pernar LI, Peyre SE, Warren LE, Gu X, Lipsitz S, Alexander EK, Ashley SW, Breen EM. Mini-clinical evaluation exercise as a student assessment tool in a surgery clerkship: lessons learned from a 5-year experience. Surgery. 2011 Aug; 150(2):272-7. 95. Abbett SK, Hevelone ND, Breen EM, Lipsitz SR, Peyre SE, Ashley SW, Smink DS. Interest in and perceived barriers to flexible-track residencies in general surgery: a national survey of residents and program directors. J Surg Educ. 2011 Sep-Oct; 68(5):365-71. 96. Ziewacz JE, Arriaga AF, Bader AM, Berry WR, Edmondson L, Wong JM, Lipsitz SR, Hepner DL, Peyre S, Nelson S, Boorman DJ, Smink DS, Ashley SW, Gawande AA. Crisis checklists for the operating room: development and pilot testing. J Am Coll Surg. 2011 Aug; 213(2):212-217.e10. 97. Peyre SE, Ashley SW. Teaching uncommon and highly complex operations: maximizing the teaching and learning. J Gastrointest Surg. 2011 Oct; 15(10):1724-5. 98. Beckitt T, Elstone A, Ashley S. Air versus physiological gas for ultrasound guided foam sclerotherapy treatment of varicose veins. Eur J Vasc Endovasc Surg. 2011 Jul; 42(1):115-9. 99. Waddell T, Kotsori A, Constantinidou A, Yousaf N, Ashley S, Parton M, Allen M, Starling N, Papadopoulos P, O'Brien M, Smith I, Johnston S. Trastuzumab beyond progression in HER2-positive advanced breast cancer: the Royal Marsden experience. Br J Cancer. 2011 May 24; 104(11):1675-9. 100. Kotsori AA, Dolly S, Sheri A, Parton M, Shaunak N, Ashley S, Walsh G, Johnston S, Smith IE. Is capecitabine efficacious in triple negative metastatic breast cancer? Oncology. 2010; 79(5-6):331-6. 101. Ashley SW. Regenerative medicine. Foreword. Curr Probl Surg. 2011 Mar; 48(3):141. 102. Pernar LI, Breen E, Ashley SW, Peyre SE. Preoperative learning goals set by surgical residents and faculty. J Surg Res. 2011 Sep; 170(1):1-5. 103. Hubner RA, Goldstein R, Mitchell S, Jones A, Ashley S, O'Brien ME, Popat S. Influence of co-morbidity on renal function assessment by Cockcroft-Gault calculation in lung cancer and mesothelioma patients receiving platinum-based chemotherapy. Lung Cancer. 2011 Sep; 73(3):356-60. 104. Cevasco M, Ashley SW. Quality measurement and improvement in general surgery. Perm J. 2011; 15(4):48-53. 105. Okines AF, Asghar U, Cunningham D, Ashley S, Ashton J, Jackson K, Hawkes E, Chau I. Rechallenge with platinum plus fluoropyrimidine +/- epirubicin in patients with oesophagogastric cancer. Oncology. 2010; 79(1-2):150-8. 106. Ashley SW. Foreword. Curr Probl Surg. 2010 Oct; 47(10):742. 107. Stain SC, Biester TW, Hanks JB, Ashley SW, Valentine RJ, Bass BL, Buyske J. Early tracking would improve the operative experience of general surgery residents. Ann Surg. 2010 Sep; 252(3):445-9; discussion 449-51. 108. Xourafas D, Lipsitz SR, Negro P, Ashley SW, Tavakkolizadeh A. Impact of mesh use on morbidity following ventral hernia repair with a simultaneous bowel resection. Arch Surg. 2010 Aug; 145(8):739-44. 109. Segal S, Gelfand BJ, Hurwitz S, Berkowitz L, Ashley SW, Nadel ES, Katz JT. Plagiarism in residency application essays. Ann Intern Med. 2010 Jul 20; 153(2):112-20. 110. Balakrishnan A, Stearns AT, Park PJ, Dreyfuss JM, Ashley SW, Rhoads DB, Tavakkolizadeh A. MicroRNA mir-16 is anti-proliferative in enterocytes and exhibits diurnal rhythmicity in intestinal crypts. Exp Cell Res. 2010 Dec 10; 316(20):3512-21. 111. Irani JL, Greenberg JA, Blanco MA, Greenberg CC, Ashley S, Lipsitz SR, Hafler JP, Breen E. Educational value of the operating room experience during a core surgical clerkship. Am J Surg. 2010 Jul; 200(1):167-72. 112. Fairweather M, Burt BM, VanderLaan PA, Brunker PA, Bafford AC, Ashley SW. Acute hemorrhage from small bowel diverticula harboring strongyloidiasis and schistosomiasis. Am Surg. 2010 May; 76(5):539-41. 113. Viswanathan SR, Khalpey Z, Ashley SW. Gallbladder lymphoma. Med Oncol. 2011 Sep; 28(3):810-2. 114. Kotsori AA, Noble JL, Ashley S, Johnston S, Smith IE. Moderate dose capecitabine in older patients with metastatic breast cancer: a standard option for first line treatment? Breast. 2010 Oct; 19(5):377-81. 115. Trani L, Myerson J, Ashley S, Young K, Sheri A, Hubner R, Puglisi M, Popat S, O'Brien ME. Histology classification is not a predictor of clinical outcomes in advanced non-small cell lung cancer (NSCLC) treated with vinorelbine or gemcitabine combinations. Lung Cancer. 2010 Nov; 70(2):200-4. 116. Balakrishnan A, Stearns AT, Ashley SW, Tavakkolizadeh A, Rhoads DB. Restricted feeding phase shifts clock gene and sodium glucose cotransporter 1 (SGLT1) expression in rats. J Nutr. 2010 May; 140(5):908-14. 117. Sutherland S, Ashley S, Miles D, Chan S, Wardley A, Davidson N, Bhatti R, Shehata M, Nouras H, Camburn T, Johnston SR. Treatment of HER2-positive metastatic breast cancer with lapatinib and capecitabine in the lapatinib expanded access programme, including efficacy in brain metastases--the UK experience. Br J Cancer. 2010 Mar 16; 102(6):995-1002. 118. Ashley SW. Foreword. Curr Probl Surg. 2010 Feb; 47(2):73. 119. Watkins DJ, Chau I, Cunningham D, Mudan SS, Karanjia N, Brown G, Ashley S, Norman AR, Gillbanks A. Defining patient outcomes in stage IV colorectal cancer: a prospective study with baseline stratification according to disease resectability status. Br J Cancer. 2010 Jan 19; 102(2):255-61. 120. Jones RL, McCall J, Adam A, O'Donnell D, Ashley S, Al-Muderis O, Thway K, Fisher C, Judson IR. Radiofrequency ablation is a feasible therapeutic option in the multi modality management of sarcoma. Eur J Surg Oncol. 2010 May; 36(5):477-82. 121. Ahmadiyeh N, Cho NL, Kellogg KC, Lipsitz SR, Moore FD, Ashley SW, Zinner MJ, Breen EM. Career satisfaction of women in surgery: perceptions, factors, and strategies. J Am Coll Surg. 2010 Jan; 210(1):23-8. 122. Greenberg CC, Ashley SW, Schrag D. Centralization of cancer surgery: what does it mean for surgical training? J Clin Oncol. 2009 Oct 01; 27(28):4637-9. 123. Garfield JM, Garfield FB, Hevelone ND, Bhattacharyya N, Dedrick DF, Ashley SW, Nadel ES, Katz JT, Kim C, Mitani AA. Doctors in acute and longitudinal care specialties emphasise different professional attributes: implications for training programmes. Med Educ. 2009 Aug; 43(8):749-56. 124. Abolmaali K, Balakrishnan A, Stearns AT, Rounds J, Rhoads DB, Ashley SW, Tavakkolizadeh A. Circadian variation in intestinal dihydropyrimidine dehydrogenase (DPD) expression: a potential mechanism for benefits of 5FU chrono-chemotherapy. Surgery. 2009 Aug; 146(2):269-73. 125. Goldstraw EJ, Castellano I, Ashley S, Allen S. The effect of Premium View post-processing software on digital mammographic reporting. Br J Radiol. 2010 Feb; 83(986):122-8. 126. Starling N, Okines A, Cunningham D, Allum W, Wotherspoon A, Benson M, Thompson J, Thomas J, Brown G, Riddell A, Stavridi F, Ashley S, Oates J, Chau I. A phase II trial of preoperative chemotherapy with epirubicin, cisplatin and capecitabine for patients with localised gastro-oesophageal junctional adenocarcinoma. Br J Cancer. 2009 Jun 02; 100(11):1725-30. 127. Messahel B, Ashley S, Saran F, Ellison D, Ironside J, Phipps K, Cox T, Chong WK, Robinson K, Picton S, Pinkerton CR, Mallucci C, Macarthur D, Jaspan T, Michalski A, Grundy RG. Relapsed intracranial ependymoma in children in the UK: patterns of relapse, survival and therapeutic outcome. Eur J Cancer. 2009 Jul; 45(10):1815-23. 128. Postel-Vinay S, Arkenau HT, Olmos D, Ang J, Barriuso J, Ashley S, Banerji U, De-Bono J, Judson I, Kaye S. Clinical benefit in Phase-I trials of novel molecularly targeted agents: does dose matter? Br J Cancer. 2009 May 05; 100(9):1373-8. 129. Greenberg JA, Ashley SW. Invited commentary. J Surg Educ. 2009 May-Jun; 66(3):132. 130. Mitchell CC, Ashley SW, Orgill DP, Zinner MJ, Raut CP. Gauging surgeons' understanding and perceptions of an academic incentive plan. Arch Surg. 2009 May; 144(5):421-6; discussion 426. 131. Rocha FG, Benoit E, Zinner MJ, Whang EE, Banks PA, Ashley SW, Mortele KJ. Impact of radiologic intervention on mortality in necrotizing pancreatitis: the role of organ failure. Arch Surg. 2009 Mar; 144(3):261-5. 132. Stearns AT, Balakrishnan A, Rhoads DB, Ashley SW, Tavakkolizadeh A. Diurnal expression of the rat intestinal sodium-glucose cotransporter 1 (SGLT1) is independent of local luminal factors. Surgery. 2009 Mar; 145(3):294-302. 133. Jones RL, Walsh G, Ashley S, Chua S, Agarwal R, O'Brien M, Johnston S, Smith IE. A randomised pilot Phase II study of doxorubicin and cyclophosphamide (AC) or epirubicin and cyclophosphamide (EC) given 2 weekly with pegfilgrastim (accelerated) vs 3 weekly (standard) for women with early breast cancer. Br J Cancer. 2009 Jan 27; 100(2):305-10. 134. Mortelé KJ, Girshman J, Szejnfeld D, Ashley SW, Erturk SM, Banks PA, Silverman SG. CT-guided percutaneous catheter drainage of acute necrotizing pancreatitis: clinical experience and observations in patients with sterile and infected necrosis. AJR Am J Roentgenol. 2009 Jan; 192(1):110-6. 135. Irani JL, Cutler CS, Whang EE, Clancy TE, Russell S, Swanson RS, Ashley SW, Zinner MJ, Raut CP. Severe acute gastrointestinal graft-vs-host disease: an emerging surgical dilemma in contemporary cancer care. Arch Surg. 2008 Nov; 143(11):1041-5; discussion 1046. 136. Stearns AT, Balakrishnan A, Rhoads DB, Ashley SW, Tavakkolizadeh A. Diurnal rhythmicity in the transcription of jejunal drug transporters. J Pharmacol Sci. 2008 Sep; 108(1):144-8. 137. Rocha FG, Balakrishnan A, Ashley SW, Clancy TE. A historic perspective on the contributions of surgeons to the understanding of acute pancreatitis. Am J Surg. 2008 Sep; 196(3):442-9. 138. Tatli S, Cizginer S, Wieczorek TJ, Ashley SW, Silverman SG. Solitary littoral cell angioma of the spleen: computed tomography and magnetic resonance imaging features. J Comput Assist Tomogr. 2008 Sep-Oct; 32(5):772-5. 139. Irani JL, Ashley SW, Brooks DC, Osteen RT, Raut CP, Russell S, Swanson RS, Whang EE, Zinner MJ, Clancy TE. Distal pancreatectomy is not associated with increased perioperative morbidity when performed as part of a multivisceral resection. J Gastrointest Surg. 2008 Dec; 12(12):2177-82. 140. Sirohi B, Arnedos M, Popat S, Ashley S, Nerurkar A, Walsh G, Johnston S, Smith IE. Platinum-based chemotherapy in triple-negative breast cancer. Ann Oncol. 2008 Nov; 19(11):1847-52. 141. Balakrishnan A, Stearns AT, Rounds J, Irani J, Giuffrida M, Rhoads DB, Ashley SW, Tavakkolizadeh A. Diurnal rhythmicity in glucose uptake is mediated by temporal periodicity in the expression of the sodium-glucose cotransporter (SGLT1). Surgery. 2008 Jun; 143(6):813-8. 142. Nicum SJ, Sutherland S, Smith IE, Ashley S, Johnston S. Determination of the rates of neurological toxicity associated with the use of dose-dense (DD) paclitaxel-containing schedules in patients with early breast cancer. J Clin Oncol. 2008 May 20; 26(15_suppl):620. 143. Sirohi B, Arnedos M, Popat S, Ashley S, Nerurkar A, Walsh G, Johnston S, Smith IE. Platinum-based chemotherapy in triple-negative (TN) breast cancer. J Clin Oncol. 2008 May 20; 26(15_suppl):1051. 144. Arkenau H, Barriuso J, Olmos D, Barlow C, De Bono JS, Judson I, Stapelton S, Hanwell J, Ashley S, Kaye SB. Prospective validation of a prognostic score to improve patient selection for phase I trials. J Clin Oncol. 2008 May 20; 26(15_suppl):2508. 145. Balakrishnan A, Stearns AT, Rhoads DB, Ashley SW, Tavakkolizadeh A. Defining the transcriptional regulation of the intestinal sodium-glucose cotransporter using RNA-interference mediated gene silencing. Surgery. 2008 Aug; 144(2):168-73. 146. Rocha FG, Sundback CA, Krebs NJ, Leach JK, Mooney DJ, Ashley SW, Vacanti JP, Whang EE. The effect of sustained delivery of vascular endothelial growth factor on angiogenesis in tissue-engineered intestine. Biomaterials. 2008 Jul; 29(19):2884-90. 147. Bigby J, Ashley SW. Disparities in surgical care: strategies for enhancing provider-patient communication. World J Surg. 2008 Apr; 32(4):529-32. 148. Behrns KE, Ashley SW, Hunter JG, Carr-Locke D. Early ERCP for gallstone pancreatitis: for whom and when? J Gastrointest Surg. 2008 Apr; 12(4):629-33. 149. Raut CP, Ashley SW. How I do it: surgical management of gastrointestinal stromal tumors. J Gastrointest Surg. 2008 Sep; 12(9):1592-9. 150. O'Brien ME, Yau T, Coward J, Hughes S, Papadopoulos P, Popat S, Norton A, Ashley S. Time and chemotherapy treatment trends in the treatment of elderly patients (age>or=70 years) with non-small cell lung cancer. Clin Oncol (R Coll Radiol). 2008 Mar; 20(2):142-7. 151. Stearns AT, Balakrishnan A, Rounds J, Rhoads DB, Ashley SW, Tavakkolizadeh A. Capsaicin-sensitive vagal afferents modulate posttranscriptional regulation of the rat Na+/glucose cotransporter SGLT1. Am J Physiol Gastrointest Liver Physiol. 2008 Apr; 294(4):G1078-83. 152. Waseem T, Duxbury M, Ito H, Ashley SW, Robinson MK. Exogenous ghrelin modulates release of pro-inflammatory and anti-inflammatory cytokines in LPS-stimulated macrophages through distinct signaling pathways. Surgery. 2008 Mar; 143(3):334-42. 153. Javid SH, Ashley S, Breen E. A colorectal curriculum for general surgery residents: are we ready for needs assessment? J Surg Educ. 2007 Nov-Dec; 64(6):324-7. 154. Wallace CA, Petrov MS, Soybel DI, Ferzoco SJ, Ashley SW, Tavakkolizadeh A. Influence of imaging on the negative appendectomy rate in pregnancy. J Gastrointest Surg. 2008 Jan; 12(1):46-50. 155. Hernandez A, Petrov MS, Brooks DC, Banks PA, Ashley SW, Tavakkolizadeh A. Acute pancreatitis and pregnancy: a 10-year single center experience. J Gastrointest Surg. 2007 Dec; 11(12):1623-7. 156. Hall GW, Katzilakis N, Pinkerton CR, Nicolin G, Ashley S, McCarthy K, Daw S, Hewitt M, Wallace WH, Shankar A. Outcome of children with nodular lymphocyte predominant Hodgkin lymphoma - a Children's Cancer and Leukaemia Group report. Br J Haematol. 2007 Sep; 138(6):761-8. 157. Greenberg JA, Irani JL, Greenberg CC, Blanco MA, Lipsitz S, Ashley SW, Breen EM, Hafler JP. The ACGME competencies in the operating room. Surgery. 2007 Aug; 142(2):180-4. 158. Dellinger EP, Tellado JM, Soto NE, Ashley SW, Barie PS, Dugernier T, Imrie CW, Johnson CD, Knaebel HP, Laterre PF, Maravi-Poma E, Kissler JJ, Sanchez-Garcia M, Utzolino S. Early antibiotic treatment for severe acute necrotizing pancreatitis: a randomized, double-blind, placebo-controlled study. Ann Surg. 2007 May; 245(5):674-83. 159. Berzin TM, Rocha FG, Whang EE, Mortele KJ, Ashley SW, Banks PA. Prevalence of primary fungal infections in necrotizing pancreatitis. Pancreatology. 2007; 7(1):63-6. 160. Mitchell CC, Ashley SW, Zinner MJ, Moore FD. Predicting future staffing needs at teaching hospitals: use of an analytical program with multiple variables. Arch Surg. 2007 Apr; 142(4):329-34. 161. Raut CP, Morgan JA, Ashley SW. Current issues in gastrointestinal stromal tumors: incidence, molecular biology, and contemporary treatment of localized and advanced disease. Curr Opin Gastroenterol. 2007 Mar; 23(2):149-58. 162. Liu JJ, Glickman JN, Li X, Maurer R, Ashley SW, Brooks DC, Carr-Locke DL, Saltzman JR. Smooth muscle remodeling of the gastroesophageal junction after endoluminal gastroplication. Gastrointest Endosc. 2007 Jun; 65(7):1023-7. 163. Foster C, Watson M, Eeles R, Eccles D, Ashley S, Davidson R, Mackay J, Morrison PJ, Hopwood P, Evans DG. Predictive genetic testing for BRCA1/2 in a UK clinical cohort: three-year follow-up. Br J Cancer. 2007 Mar 12; 96(5):718-24. 164. Aylin P, Lees T, Baker S, Prytherch D, Ashley S. Descriptive study comparing routine hospital administrative data with the Vascular Society of Great Britain and Ireland's National Vascular Database. Eur J Vasc Endovasc Surg. 2007 Apr; 33(4):461-5; discussion 466. 165. Liau SS, Ashley SW, Whang EE. Lentivirus-mediated RNA interference of HMGA1 promotes chemosensitivity to gemcitabine in pancreatic adenocarcinoma. J Gastrointest Surg. 2006 Nov; 10(9):1254-62; discussion 1263. 166. della Rovere GQ, Bonomi R, Ashley S, Benson JR. Axillary staging in women with small invasive breast tumours. Eur J Surg Oncol. 2006 Sep; 32(7):733-7. 167. Kuciejewska A, Banerji U, Walsh G, Ashley S, O'Brien M, Johnston S, Smith I. A study of factors determining outcome of patients receiving third line chemotherapy for metastatic breast cancer: The Royal Marsden Hospital experience. J Clin Oncol. 2006 Jun 20; 24(18_suppl):657. 168. Karavasilis V, Seddon B, Al-Muderis O, Ashley S, Judson I. Role of palliative chemotherapy in advanced soft tissue sarcoma: Retrospective analysis of 488 patients. J Clin Oncol. 2006 Jun 20; 24(18_suppl):9520. 169. Dignan F, Alvares C, Riley U, Ethell M, Cunningham D, Treleaven J, Ashley S, Bendig J, Morgan G, Potter M. Parainfluenza type 3 infection post stem cell transplant: high prevalence but low mortality. J Hosp Infect. 2006 Aug; 63(4):452-8. 170. Raut CP, Kulke MH, Glickman JN, Swanson RS, Ashley SW. Carcinoid tumors. Curr Probl Surg. 2006 Jun; 43(6):383-450. 171. Minniti G, Traish D, Ashley S, Gonsalves A, Brada M. Fractionated stereotactic conformal radiotherapy for secreting and nonsecreting pituitary adenomas. Clin Endocrinol (Oxf). 2006 May; 64(5):542-8. 172. Matros E, Rocha F, Zinner M, Wang J, Ashley S, Breen E, Soybel D, Shoji B, Burgess A, Bleday R, Kuntz R, Whang E. Does gum chewing ameliorate postoperative ileus? Results of a prospective, randomized, placebo-controlled trial. J Am Coll Surg. 2006 May; 202(5):773-8. 173. Modi BP, Owens C, Ashley SW, Colson YL. Bouveret meets Boerhaave. Ann Thorac Surg. 2006 Apr; 81(4):1493-5. 174. Banerjee S, Reis-Filho JS, Ashley S, Steele D, Ashworth A, Lakhani SR, Smith IE. Basal-like breast carcinomas: clinical outcome and response to chemotherapy. J Clin Pathol. 2006 Jul; 59(7):729-35. 175. Liu JJ, Carr-Locke DL, Osterman MT, Li X, Maurer R, Brooks DC, Ashley SW, Saltzman JR. Endoscopic treatment for atypical manifestations of gastroesophageal reflux disease. Am J Gastroenterol. 2006 Mar; 101(3):440-5. 176. Kellogg KC, Breen E, Ferzoco SJ, Zinner MJ, Ashley SW. Resistance to change in surgical residency: an ethnographic study of work hours reform. J Am Coll Surg. 2006 Apr; 202(4):630-6. 177. Jones RL, Lakhani SR, Ring AE, Ashley S, Walsh G, Smith IE. Pathological complete response and residual DCIS following neoadjuvant chemotherapy for breast carcinoma. Br J Cancer. 2006 Feb 13; 94(3):358-62. 178. Matros E, Bailey G, Clancy T, Zinner M, Ashley S, Whang E, Redston M. Cytokeratin 20 expression identifies a subtype of pancreatic adenocarcinoma with decreased overall survival. Cancer. 2006 Feb 01; 106(3):693-702. 179. Watson M, St James-Roberts I, Ashley S, Tilney C, Brougham B, Edwards L, Baldus C, Romer G. Factors associated with emotional and behavioural problems among school age children of breast cancer patients. Br J Cancer. 2006 Jan 16; 94(1):43-50. 180. Yau T, Ashley S, Popat S, Norton A, Matakidou A, Coward J, O'Brien ME. Time and chemotherapy treatment trends in the treatment of elderly patients (age >/=70 years) with small cell lung cancer. Br J Cancer. 2006 Jan 16; 94(1):18-21. 181. Breen E, Irani JL, Mello MM, Whang EE, Zinner MJ, Ashley SW. The future of surgery: today's residents speak. Curr Surg. 2005 Sep-Oct; 62(5):543-6. 182. Perez A, Ito H, Farivar RS, Cohn LH, Byrne JG, Rawn JD, Aranki SF, Zinner MJ, Tilney NL, Brooks DC, Ashley SW, Banks PA, Whang EE. Risk factors and outcomes of pancreatitis after open heart surgery. Am J Surg. 2005 Sep; 190(3):401-5. 183. Tavakkolizadeh A, Ramsanahie A, Levitsky LL, Zinner MJ, Whang EE, Ashley SW, Rhoads DB. Differential role of vagus nerve in maintaining diurnal gene expression rhythms in the proximal small intestine. J Surg Res. 2005 Nov; 129(1):73-8. 184. Irani JL, Mello MM, Ashley SW, Whang EE, Zinner MJ, Breen E. Surgical residents' perceptions of the effects of the ACGME duty hour requirements 1 year after implementation. Surgery. 2005 Aug; 138(2):246-53. 185. Clancy TE, Ashley SW. Pancreaticoduodenectomy (Whipple operation). Surg Oncol Clin N Am. 2005 Jul; 14(3):533-52, vii. 186. Duxbury MS, Ashley SW, Whang EE. RNA interference: a mammalian SID-1 homologue enhances siRNA uptake and gene silencing efficacy in human cells. Biochem Biophys Res Commun. 2005 Jun 03; 331(2):459-63. 187. Yau T, Ashley S, Popat S, Norton A, Matakidou A, Priest K, James M, O'Brien ME. Case-control study comparing the cisplatin-based chemotherapy toxicity between elderly (age>/=70) and younger patient with lung cancer. J Clin Oncol. 2005 Jun; 23(16_suppl):7239. 188. Sirohi B, Matakidou A, Ashley S, Popat S, Saka W, Priest K, Norton A, James M, Benepal T, Eisen T, O'Brien M. Early response to platinum-based chemotherapy in non small cell lung cancer (NSCLC) predicts survival. J Clin Oncol. 2005 Jun; 23(16_suppl):7208. 189. Brada M, Ashley S, Dowe A, Gonsalves A, Huchet A, Pesce G, Reni M, Saran F, Wharram B, Wilkins M, Wilkins P. Neoadjuvant phase II multicentre study of new agents in patients with malignant glioma after minimal surgery. Report of a cohort of 187 patients treated with temozolomide. Ann Oncol. 2005 Jun; 16(6):942-9. 190. Duxbury MS, Ito H, Benoit E, Waseem T, Ashley SW, Whang EE. RNA interference demonstrates a novel role for integrin-linked kinase as a determinant of pancreatic adenocarcinoma cell gemcitabine chemoresistance. Clin Cancer Res. 2005 May 01; 11(9):3433-8. 191. Clancy TE, Benoit EP, Ashley SW. Current management of acute pancreatitis. J Gastrointest Surg. 2005 Mar; 9(3):440-52. 192. Perez A, Duxbury M, Rocha FG, Ramsanahie AP, Farivar RS, Varnholt H, Ito H, Wong H, Rounds J, Zinner MJ, Whang EE, Ashley SW. Glucagon-like peptide 2 is an endogenous mediator of postresection intestinal adaptation. JPEN J Parenter Enteral Nutr. 2005 Mar-Apr; 29(2):97-101. 193. Duxbury MS, Matros E, Clancy T, Bailey G, Doff M, Zinner MJ, Ashley SW, Maitra A, Redston M, Whang EE. CEACAM6 is a novel biomarker in pancreatic adenocarcinoma and PanIN lesions. Ann Surg. 2005 Mar; 241(3):491-6. 194. Ring AE, Smith IE, Ashley S, Fulford LG, Lakhani SR. Oestrogen receptor status, pathological complete response and prognosis in patients receiving neoadjuvant chemotherapy for early breast cancer. Br J Cancer. 2004 Dec 13; 91(12):2012-7. 195. Ito H, Clancy TE, Osteen RT, Swanson RS, Bueno R, Sugarbaker DJ, Ashley SW, Zinner MJ, Whang EE. Adenocarcinoma of the gastric cardia: what is the optimal surgical approach? J Am Coll Surg. 2004 Dec; 199(6):880-6. 196. Minniti G, Traish D, Ashley S, Gonsalves A, Brada M. Risk of second brain tumor after conservative surgery and radiotherapy for pituitary adenoma: update after an additional 10 years. J Clin Endocrinol Metab. 2005 Feb; 90(2):800-4. 197. Watson M, Foster C, Eeles R, Eccles D, Ashley S, Davidson R, Mackay J, Morrison PJ, Hopwood P, Evans DG. Psychosocial impact of breast/ovarian (BRCA1/2) cancer-predictive genetic testing in a UK multi-centre clinical cohort. Br J Cancer. 2004 Nov 15; 91(10):1787-94. 198. Ramsanahie AP, Berger UV, Zinner MJ, Whang EE, Rhoads DB, Ashley SW. Effect of glucagon-like peptide-2 (GLP-2) on diurnal SGLT1 expression. Dig Dis Sci. 2004 Nov-Dec; 49(11-12):1731-7. 199. Ito H, Duxbury M, Benoit E, Clancy TE, Zinner MJ, Ashley SW, Whang EE. Prostaglandin E2 enhances pancreatic cancer invasiveness through an Ets-1-dependent induction of matrix metalloproteinase-2. Cancer Res. 2004 Oct 15; 64(20):7439-46. 200. Duxbury MS, Ito H, Benoit E, Ashley SW, Whang EE. CEACAM6 is a determinant of pancreatic adenocarcinoma cellular invasiveness. Br J Cancer. 2004 Oct 04; 91(7):1384-90. 201. Duxbury MS, Matros E, Ito H, Zinner MJ, Ashley SW, Whang EE. Systemic siRNA-mediated gene silencing: a new approach to targeted therapy of cancer. Ann Surg. 2004 Oct; 240(4):667-74; discussion 675-6. 202. Rocha FG, Shen KR, Jasleen J, Tavakkolizadeh A, Zinner MJ, Whang EE, Ashley SW. Glucagon-like peptide-2: divergent signaling pathways. J Surg Res. 2004 Sep; 121(1):5-12. 203. Ito H, Duxbury M, Zinner MJ, Ashley SW, Whang EE. Glucose transporter-1 gene expression is associated with pancreatic cancer invasiveness and MMP-2 activity. Surgery. 2004 Sep; 136(3):548-56. 204. Andreopoulou E, Ross PJ, O'Brien ME, Ford HE, Priest K, Eisen T, Norton A, Ashley S, Smith IE. The palliative benefits of MVP (mitomycin C, vinblastine and cisplatin) chemotherapy in patients with malignant mesothelioma. Ann Oncol. 2004 Sep; 15(9):1406-12. 205. Duxbury MS, Ito H, Zinner MJ, Ashley SW, Whang EE. Ligation of EphA2 by Ephrin A1-Fc inhibits pancreatic adenocarcinoma cellular invasiveness. Biochem Biophys Res Commun. 2004 Aug 06; 320(4):1096-102. 206. Duxbury MS, Ito H, Benoit E, Zinner MJ, Ashley SW, Whang EE. Retrovirally mediated RNA interference targeting the M2 subunit of ribonucleotide reductase: A novel therapeutic strategy in pancreatic cancer. Surgery. 2004 Aug; 136(2):261-9. 207. Duxbury MS, Ito H, Benoit E, Zinner MJ, Ashley SW, Whang EE. Overexpression of CEACAM6 promotes insulin-like growth factor I-induced pancreatic adenocarcinoma cellular invasiveness. Oncogene. 2004 Jul 29; 23(34):5834-42. 208. Parton M, Maisey N, Banerjee S, Harper-Wynne C, Sumpter K, Ashley S, Eisen T, Obrien M. Gefitinib in patients with non-small cell lung cancer (NSCLC): The Royal Marsden experience. J Clin Oncol. 2004 Jul 15; 22(14_suppl):7099. 209. Duxbury MS, Ito H, Zinner MJ, Ashley SW, Whang EE. siRNA directed against c-Src enhances pancreatic adenocarcinoma cell gemcitabine chemosensitivity. J Am Coll Surg. 2004 Jun; 198(6):953-9. 210. Duxbury MS, Ito H, Benoit E, Waseem T, Ashley SW, Whang EE. A novel role for carcinoembryonic antigen-related cell adhesion molecule 6 as a determinant of gemcitabine chemoresistance in pancreatic adenocarcinoma cells. Cancer Res. 2004 Jun 01; 64(11):3987-93. 211. Ito H, Duxbury M, Benoit E, Farivar RS, Gardner-Thorpe J, Zinner MJ, Ashley SW, Whang EE. Fibronectin-induced COX-2 mediates MMP-2 expression and invasiveness of rhabdomyosarcoma. Biochem Biophys Res Commun. 2004 May 28; 318(2):594-600. 212. Ross PJ, Ashley S, Norton A, Priest K, Waters JS, Eisen T, Smith IE, O'Brien ME. Do patients with weight loss have a worse outcome when undergoing chemotherapy for lung cancers? Br J Cancer. 2004 May 17; 90(10):1905-11. 213. Duxbury MS, Ito H, Ashley SW, Whang EE. CEACAM6 as a novel target for indirect type 1 immunotoxin-based therapy in pancreatic adenocarcinoma. Biochem Biophys Res Commun. 2004 May 07; 317(3):837-43. 214. Duxbury MS, Ito H, Zinner MJ, Ashley SW, Whang EE. Focal adhesion kinase gene silencing promotes anoikis and suppresses metastasis of human pancreatic adenocarcinoma cells. Surgery. 2004 May; 135(5):555-62. 215. Duxbury MS, Grikscheit TC, Gardner-Thorpe J, Rocha FG, Ito H, Perez A, Ashley SW, Vacanti JP, Whang EE. Lymphangiogenesis in tissue-engineered small intestine. Transplantation. 2004 Apr 27; 77(8):1162-6. 216. Duxbury MS, Ito H, Ashley SW, Whang EE. c-Src-dependent cross-talk between CEACAM6 and alphavbeta3 integrin enhances pancreatic adenocarcinoma cell adhesion to extracellular matrix components. Biochem Biophys Res Commun. 2004 Apr 23; 317(1):133-41. 217. Duxbury MS, Ito H, Zinner MJ, Ashley SW, Whang EE. Inhibition of SRC tyrosine kinase impairs inherent and acquired gemcitabine resistance in human pancreatic adenocarcinoma cells. Clin Cancer Res. 2004 Apr 01; 10(7):2307-18. 218. Duxbury MS, Ito H, Ashley SW, Whang EE. CEACAM6 cross-linking induces caveolin-1-dependent, Src-mediated focal adhesion kinase phosphorylation in BxPC3 pancreatic adenocarcinoma cells. J Biol Chem. 2004 May 28; 279(22):23176-82. 219. Saund MS, Demetri GD, Ashley SW. Gastrointestinal stromal tumors (GISTs). Curr Opin Gastroenterol. 2004 Mar; 20(2):89-94. 220. Duxbury MS, Ito H, Zinner MJ, Ashley SW, Whang EE. RNA interference targeting the M2 subunit of ribonucleotide reductase enhances pancreatic adenocarcinoma chemosensitivity to gemcitabine. Oncogene. 2004 Feb 26; 23(8):1539-48. 221. Ito H, Osteen RT, Bleday R, Zinner MJ, Ashley SW, Whang EE. Appendiceal adenocarcinoma: long-term outcomes after surgical therapy. Dis Colon Rectum. 2004 Apr; 47(4):474-80. 222. Duxbury MS, Ito H, Zinner MJ, Ashley SW, Whang EE. EphA2: a determinant of malignant cellular behavior and a potential therapeutic target in pancreatic adenocarcinoma. Oncogene. 2004 Feb 19; 23(7):1448-56. 223. Ito H, Matros E, Brooks DC, Osteen RT, Zinner MJ, Swanson RS, Ashley SW, Whang EE. Treatment outcomes associated with surgery for gallbladder cancer: a 20-year experience. J Gastrointest Surg. 2004 Feb; 8(2):183-90. 224. Duxbury MS, Ashley SW, Whang EE. Inhibition of pancreatic adenocarcinoma cellular invasiveness by blebbistatin: a novel myosin II inhibitor. Biochem Biophys Res Commun. 2004 Jan 23; 313(4):992-7. 225. Duxbury MS, Ito H, Zinner MJ, Ashley SW, Whang EE. CEACAM6 gene silencing impairs anoikis resistance and in vivo metastatic ability of pancreatic adenocarcinoma cells. Oncogene. 2004 Jan 15; 23(2):465-73. 226. Foster C, Evans DG, Eeles R, Eccles D, Ashley S, Brooks L, Cole T, Cook J, Davidson R, Gregory H, Mackay J, Morrison PJ, Watson M. Non-uptake of predictive genetic testing for BRCA1/2 among relatives of known carriers: attributes, cancer worry, and barriers to testing in a multicenter clinical cohort. Genet Test. 2004; 8(1):23-9. 227. Ring A, Webb A, Ashley S, Allum WH, Ebbs S, Gui G, Sacks NP, Walsh G, Smith IE. Is surgery necessary after complete clinical remission following neoadjuvant chemotherapy for early breast cancer? J Clin Oncol. 2003 Dec 15; 21(24):4540-5. 228. Farivar RS, Gardner-Thorpe J, Ito H, Arshad H, Zinner MJ, Ashley SW, Whang EE. The efficacy of tyrosine kinase inhibitors on human pancreatic cancer cell lines. J Surg Res. 2003 Dec; 115(2):219-25. 229. Gardner-Thorpe J, Grikscheit TC, Ito H, Perez A, Ashley SW, Vacanti JP, Whang EE. Angiogenesis in tissue-engineered small intestine. Tissue Eng. 2003 Dec; 9(6):1255-61. 230. Murray PV, O'Brien ME, Sayer R, Cooke N, Knowles G, Miller AC, Varney V, Rowell NP, Padhani AR, MacVicar D, Norton A, Ashley S, Smith IE. The pathway study: results of a pilot feasibility study in patients suspected of having lung carcinoma investigated in a conventional chest clinic setting compared to a centralised two-stop pathway. Lung Cancer. 2003 Dec; 42(3):283-90. 231. Duxbury MS, Ito H, Benoit E, Zinner MJ, Ashley SW, Whang EE. RNA interference targeting focal adhesion kinase enhances pancreatic adenocarcinoma gemcitabine chemosensitivity. Biochem Biophys Res Commun. 2003 Nov 21; 311(3):786-92. 232. Gardner-Thorpe J, Ito H, Ashley SW, Whang EE. Ribosomal protein P2: a potential molecular target for antisense therapy of human malignancies. Anticancer Res. 2003 Nov-Dec; 23(6C):4549-60. 233. Ito H, Perez A, Brooks DC, Osteen RT, Zinner MJ, Moore FD, Ashley SW, Whang EE. Surgical treatment of small bowel cancer: a 20-year single institution experience. J Gastrointest Surg. 2003 Nov; 7(7):925-30. 234. Shannon C, Ashley S, Smith IE. Does timing of adjuvant chemotherapy for early breast cancer influence survival? J Clin Oncol. 2003 Oct 15; 21(20):3792-7. 235. Whang EE, Perez A, Ito H, Mello MM, Ashley SW, Zinner MJ. Work hours reform: perceptions and desires of contemporary surgical residents. J Am Coll Surg. 2003 Oct; 197(4):624-30. 236. Duxbury MS, Waseem T, Ito H, Robinson MK, Zinner MJ, Ashley SW, Whang EE. Ghrelin promotes pancreatic adenocarcinoma cellular proliferation and invasiveness. Biochem Biophys Res Commun. 2003 Sep 19; 309(2):464-8. 237. Archer CD, Parton M, Smith IE, Ellis PA, Salter J, Ashley S, Gui G, Sacks N, Ebbs SR, Allum W, Nasiri N, Dowsett M. Early changes in apoptosis and proliferation following primary chemotherapy for breast cancer. Br J Cancer. 2003 Sep 15; 89(6):1035-41. 238. Ferzoco SJ, Matros E, Ashley SW. Electrical stimulation for gastroparesis: wired for success or just wired? JPEN J Parenter Enteral Nutr. 2003 Sep-Oct; 27(5):386-7. 239. Ramsanahie A, Duxbury MS, Grikscheit TC, Perez A, Rhoads DB, Gardner-Thorpe J, Ogilvie J, Ashley SW, Vacanti JP, Whang EE. Effect of GLP-2 on mucosal morphology and SGLT1 expression in tissue-engineered neointestine. Am J Physiol Gastrointest Liver Physiol. 2003 Dec; 285(6):G1345-52. 240. Ito H, Gardner-Thorpe J, Zinner MJ, Ashley SW, Whang EE. Inhibition of tyrosine kinase Src suppresses pancreatic cancer invasiveness. Surgery. 2003 Aug; 134(2):221-6. 241. Gardner-Thorpe J, Ito H, Ashley SW, Whang EE. Autoantibody-mediated inhibition of pancreatic cancer cell growth in an athymic (nude) mouse model. Pancreas. 2003 Aug; 27(2):180-9. 242. McAleese JJ, Stenning SP, Ashley S, Traish D, Hines F, Sardell S, Guerrero D, Brada M. Hypofractionated radiotherapy for poor prognosis malignant glioma: matched pair survival analysis with MRC controls. Radiother Oncol. 2003 May; 67(2):177-82. 243. Perez A, Saltzman JR, Carr-Locke DL, Brooks DC, Osteen RT, Zinner MJ, Ashley SW, Whang EE. Benign nonampullary duodenal neoplasms. J Gastrointest Surg. 2003 May-Jun; 7(4):536-41. 244. Querci della Rovere G, Ahmad I, Singh P, Ashley S, Daniels IR, Mortimer P. An audit of the incidence of arm lymphoedema after prophylactic level I/II axillary dissection without division of the pectoralis minor muscle. Ann R Coll Surg Engl. 2003 May; 85(3):158-61. 245. Whang EE, Mello MM, Ashley SW, Zinner MJ. Implementing resident work hour limitations: lessons from the New York State experience. Ann Surg. 2003 Apr; 237(4):449-55. 246. Shankar AG, Ashley S, Craft AW, Pinkerton CR. Outcome after relapse in an unselected cohort of children and adolescents with Ewing sarcoma. Med Pediatr Oncol. 2003 Mar; 40(3):141-7. 247. Tavakkolizadeh A, Berger UV, Stephen AE, Kim BS, Mooney D, Hediger MA, Ashley SW, Vacanti JP, Whang EE. Tissue-engineered neomucosa: morphology, enterocyte dynamics, and SGLT1 expression topography. Transplantation. 2003 Jan 27; 75(2):181-5. 248. Cuzick J, Powles T, Veronesi U, Forbes J, Edwards R, Ashley S, Boyle P. Overview of the main outcomes in breast-cancer prevention trials. Lancet. 2003 Jan 25; 361(9354):296-300. 249. Perez A, Zinner MJ, Ashley SW, Brooks DC, Whang EE. What is the value of telerobotic technology in gastrointestinal surgery? Surg Endosc. 2003 May; 17(5):811-3. 250. Brada M, Ashley S, Ford D, Traish D, Burchell L, Rajan B. Cerebrovascular mortality in patients with pituitary adenoma. Clin Endocrinol (Oxf). 2002 Dec; 57(6):713-7. 251. Ashley SW, Lauwers GY. Case records of the Massachusetts General Hospital. Weekly clinicopathological exercises. Case 37-2002. A 69-year-old man with painful cutaneous nodules, elevated lipase levels, and abnormal results on abdominal scanning. N Engl J Med. 2002 Nov 28; 347(22):1783-91. 252. Perez A, Whang EE, Brooks DC, Moore FD, Hughes MD, Sica GT, Zinner MJ, Ashley SW, Banks PA. Is severity of necrotizing pancreatitis increased in extended necrosis and infected necrosis? Pancreas. 2002 Oct; 25(3):229-33. 253. Perez A, Grikscheit TC, Blumberg RS, Ashley SW, Vacanti JP, Whang EE. Tissue-engineered small intestine: ontogeny of the immune system. Transplantation. 2002 Sep 15; 74(5):619-23. 254. Ramsanahie AP, Perez A, Duensing AU, Zinner MJ, Ashley SW, Whang EE. Glucagon-like peptide 2 enhances intestinal epithelial restitution. J Surg Res. 2002 Sep; 107(1):44-9. 255. Cosgrove CM, Thornberry DJ, Wilkins DC, Ashley S. Surgical experience and supervision may influence the quality of lower limb amputation. Ann R Coll Surg Engl. 2002 Sep; 84(5):344-7. 256. Secor SM, Lane JS, Whang EE, Ashley SW, Diamond J. Luminal nutrient signals for intestinal adaptation in pythons. Am J Physiol Gastrointest Liver Physiol. 2002 Dec; 283(6):G1298-309. 257. De Boer RH, Eisen TG, Ellis PA, Johnston SR, Walsh G, Ashley S, Smith IE. A randomised phase II study of conventional versus accelerated infusional chemotherapy with granulocyte colony-stimulating factor support in advanced breast cancer. Ann Oncol. 2002 Jun; 13(6):889-94. 258. Rogers SO, Lee MC, Ashley SW. Giant colonic lipoma as lead point for intermittent colo-colonic intussusception. Surgery. 2002 Jun; 131(6):687-8. 259. Jasleen J, Ashley SW, Shimoda N, Zinner MJ, Whang EE. Glucagon-like peptide 2 stimulates intestinal epithelial proliferation in vitro. Dig Dis Sci. 2002 May; 47(5):1135-40. 260. Trent S, Kong A, Short SC, Traish D, Ashley S, Dowe A, Hines F, Brada M. Temozolomide as second-line chemotherapy for relapsed gliomas. J Neurooncol. 2002 May; 57(3):247-51. 261. Gardner-Thorpe J, Ito H, Ashley SW, Whang EE. Differential display of expressed genes in pancreatic cancer cells. Biochem Biophys Res Commun. 2002 Apr 26; 293(1):391-5. 262. Foster C, Evans DG, Eeles R, Eccles D, Ashley S, Brooks L, Davidson R, Mackay J, Morrison PJ, Watson M. Predictive testing for BRCA1/2: attributes, risk perception and management in a multi-centre clinical cohort. Br J Cancer. 2002 Apr 22; 86(8):1209-16. 263. Jalali R, Loughrey C, Baumert B, Perks J, Warrington AP, Traish D, Ashley S, Brada M. High precision focused irradiation in the form of fractionated stereotactic conformal radiotherapy (SCRT) for benign meningiomas predominantly in the skull base location. Clin Oncol (R Coll Radiol). 2002 Apr; 14(2):103-9. 264. Mendes R, O'Brien ME, Mitra A, Norton A, Gregory RK, Padhani AR, Bromelow KV, Winkley AR, Ashley S, Smith IE, Souberbielle BE. Clinical and immunological assessment of Mycobacterium vaccae (SRL172) with chemotherapy in patients with malignant mesothelioma. Br J Cancer. 2002 Feb 01; 86(3):336-41. 265. Clancy TE, Ashley SW. Current management of necrotizing pancreatitis. Adv Surg. 2002; 36:103-21. 266. Ashley SW, Perez A, Pierce EA, Brooks DC, Moore FD, Whang EE, Banks PA, Zinner MJ. Necrotizing pancreatitis: contemporary analysis of 99 consecutive cases. Ann Surg. 2001 Oct; 234(4):572-9; discussion 579-80. 267. Rongione AJ, Kusske AM, Newton TR, Ashley SW, Zinner MJ, Mcfadden DW. EGF and TGF stimulate proabsorption of glucose and electrolytes by Na+/glucose cotransporter in awake canine model. Dig Dis Sci. 2001 Aug; 46(8):1740-7. 268. Lane JS, Todd KE, Gloor B, Chandler CF, Kau AW, Ashley SW, Reber HA, McFadden DW. Platelet activating factor antagonism reduces the systemic inflammatory response in a murine model of acute pancreatitis. J Surg Res. 2001 Aug; 99(2):365-70. 269. Cosgrove C, Ashley S. Randomized prospective study comparing preoperative epidural and intraoperative perineural analgesia for the prevention of postoperative stump and phantom limb pain following major amputation. Reg Anesth Pain Med. 2001 Jul-Aug; 26(4):316-21. 270. Murray PV, O'Brien ME, Padhani AR, Powles R, Cunningham D, Jeanes A, Ashley S. Use of first line bronchoalveolar lavage in the immunosuppressed oncology patient. Bone Marrow Transplant. 2001 May; 27(9):967-71. 271. Smith IE, O'Brien ME, Talbot DC, Nicolson MC, Mansi JL, Hickish TF, Norton A, Ashley S. Duration of chemotherapy in advanced non-small-cell lung cancer: a randomized trial of three versus six courses of mitomycin, vinblastine, and cisplatin. J Clin Oncol. 2001 Mar 01; 19(5):1336-43. 272. Tavakkolizadeh A, Berger UV, Shen KR, Levitsky LL, Zinner MJ, Hediger MA, Ashley SW, Whang EE, Rhoads DB. Diurnal rhythmicity in intestinal SGLT-1 function, V(max), and mRNA expression topography. Am J Physiol Gastrointest Liver Physiol. 2001 Feb; 280(2):G209-15. 273. Kyriakides C, Jasleen J, Wang Y, Moore FD, Ashley SW, Hechtman HB. Neutrophils, not complement, mediate the mortality of experimental hemorrhagic pancreatitis. Pancreas. 2001 Jan; 22(1):40-6. 274. Jyothirmayi R, Saran FH, Jalali R, Perks J, Warrington AP, Traish D, Ashley S, Hines F, Brada M. Stereotactic radiotherapy for solitary brain metastases. Clin Oncol (R Coll Radiol). 2001; 13(3):228-34. 275. Tavakkolizadeh A, Shen R, Jasleen J, Soybel DI, Jacobs DO, Zinner MJ, Ashley SW, Whang EE. Effect of growth hormone on intestinal Na+/glucose cotransporter activity. JPEN J Parenter Enteral Nutr. 2001 Jan-Feb; 25(1):18-22. 276. Shimoda N, Jasleen J, Rounds JD, Ashley SW, Jacobs DO. Sepsis increases the plasma membrane content of alpha1 and alpha2 isoforms of Na+-K+ adenosine triphosphatase in rat skeletal muscle. Arch Surg. 2001 Jan; 136(1):95-100. 277. Gregory RK, Smith IE, Norton A, Ashley S, O'Brien ME. Mitomycin C, vinblastine and carboplatin: effective outpatient chemotherapy for advanced non-small cell carcinoma of the lung (NSCLC). Clin Oncol (R Coll Radiol). 2001; 13(6):483-7. 278. Secor SM, Whang EE, Lane JS, Ashley SW, Diamond J. Luminal and systemic signals trigger intestinal adaptation in the juvenile python. Am J Physiol Gastrointest Liver Physiol. 2000 Dec; 279(6):G1177-87. 279. Murray PV, Soussi T, O'Brien ME, Smith IE, Brossault S, Norton A, Ashley S, Tavassoli M. Serum p53 antibodies: predictors of survival in small-cell lung cancer? Br J Cancer. 2000 Dec; 83(11):1418-24. 280. McCarthy RJ, Neary W, Roobottom C, Tottle A, Ashley S. Short-term results of femoropopliteal subintimal angioplasty. Br J Surg. 2000 Oct; 87(10):1361-5. 281. Chandler CF, Lane JS, Ferguson P, Thompson JE, Ashley SW. Prospective evaluation of early versus delayed laparoscopic cholecystectomy for treatment of acute cholecystitis. Am Surg. 2000 Sep; 66(9):896-900. 282. De Boer RH, Allum WH, Ebbs SR, Gui GP, Johnston SR, Sacks NP, Walsh G, Ashley S, Smith IE. Multimodality therapy in inflammatory breast cancer: is there a place for surgery? Ann Oncol. 2000 Sep; 11(9):1147-53. 283. Tavakkolizadeh A, Shen R, Abraham P, Kormi N, Seifert P, Edelman ER, Jacobs DO, Zinner MJ, Ashley SW, Whang EE. Glucagonlike peptide 2 (glp-2) promotes intestinal recovery following chemotherapy-induced enteritis. Curr Surg. 2000 Sep 01; 57(5):502. 284. Whang EE, Danial T, Dunn JC, Ashley SW, Reber HA, Lewin TJ, Tompkins RK. The spectrum of mucin-producing adenocarcinoma of the pancreas. Pancreas. 2000 Aug; 21(2):147-51. 285. Saso R, Kulkarni S, Mitchell P, Treleaven J, Swansbury GJ, Mehta J, Powles R, Ashley S, Kuan A, Powles T. Secondary myelodysplastic syndrome/acute myeloid leukaemia following mitoxantrone-based therapy for breast carcinoma. Br J Cancer. 2000 Jul; 83(1):91-4. 286. Tavakkolizadeh A, Shen R, Abraham P, Kormi N, Seifert P, Edelman ER, Jacobs DO, Zinner MJ, Ashley SW, Whang EE. Glucagon-like peptide 2: a new treatment for chemotherapy-induced enteritis. J Surg Res. 2000 Jun 01; 91(1):77-82. 287. Linden PA, Ashley SW. Mucinous cystadenocarcinoma of the mesentery. Surgery. 2000 Jun; 127(6):707-8. 288. Jasleen J, Shimoda N, Shen ER, Tavakkolizadeh A, Whang EE, Jacobs DO, Zinner MJ, Ashley SW. Signaling mechanisms of glucagon-like peptide 2-induced intestinal epithelial cell proliferation. J Surg Res. 2000 May 01; 90(1):13-8. 289. Westbury C, Hines F, Hawkes E, Ashley S, Brada M. Advice on hair and scalp care during cranial radiotherapy: a prospective randomized trial. Radiother Oncol. 2000 Feb; 54(2):109-16. 290. Breen EM, Ashley SW. Laparoscopic surgery for Crohn's disease?--a conditional yes. Inflamm Bowel Dis. 2000 Feb; 6(1):43-5; discussion 46-7. 291. Lewis MP, Lo SK, Reber PU, Patel A, Gloor B, Todd KE, Toyama MT, Sherman S, Ashley SW, Reber HA. Endoscopic measurement of pancreatic tissue perfusion in patients with chronic pancreatitis and control patients. Gastrointest Endosc. 2000 Feb; 51(2):195-9. 292. Hines OJ, Whang EE, Bilchik AJ, Zinner MJ, Welton ML, Lane J, McFadden DW, Ashley SW. Role of Na+-glucose cotransport in jejunal meal-induced absorption. Dig Dis Sci. 2000 Jan; 45(1):1-6. 293. Gregory RK, Powles TJ, Salter J, Chang JC, Ashley S, Dowsett M. Prognostic relevance of cerbB2 expression following neoadjuvant chemotherapy in patients in a randomised trial of neoadjuvant versus adjuvant chemoendocrine therapy. Breast Cancer Res Treat. 2000 Jan; 59(2):171-5. 294. Rongione AJ, Kusske AM, Kwan K, Ashley SW, Reber HA, McFadden DW. Interleukin-10 protects against lethality of intra-abdominal infection and sepsis. J Gastrointest Surg. 2000 Jan-Feb; 4(1):70-6. 295. Assersohn L, Powles TJ, Ashley S, Nash AG, Neal AJ, Sacks N, Chang J, Querci della Rovere U, Naziri N. Local relapse in primary breast cancer patients with unexcised positive surgical margins after lumpectomy, radiotherapy and chemoendocrine therapy. Ann Oncol. 1999 Dec; 10(12):1451-5. 296. Patel AG, Reber PU, Toyama MT, Ashley SW, Reber HA. Effect of pancreaticojejunostomy on fibrosis, pancreatic blood flow, and interstitial pH in chronic pancreatitis: a feline model. Ann Surg. 1999 Nov; 230(5):672-9. 297. Shankar AG, Pinkerton CR, Atra A, Ashley S, Lewis I, Spooner D, Cannon S, Grimer R, Cotterill SJ, Craft AW. Local therapy and other factors influencing site of relapse in patients with localised Ewing's sarcoma. United Kingdom Children's Cancer Study Group (UKCCSG). Eur J Cancer. 1999 Nov; 35(12):1698-704. 298. Brada M, Burchell L, Ashley S, Traish D. The incidence of cerebrovascular accidents in patients with pituitary adenoma. Int J Radiat Oncol Biol Phys. 1999 Oct 01; 45(3):693-8. 299. McKinna F, Gothard L, Ashley S, Ebbs S, Yarnold J. Selective avoidance of lymphatic radiotherapy in the conservative management of women with early breast cancer. Radiother Oncol. 1999 Sep; 52(3):219-23. 300. McKinna F, Gothard L, Ashley S, Ebbs SR, Yarnold JR. Lymphatic relapse in women with early breast cancer: a difficult management problem. Eur J Cancer. 1999 Jul; 35(7):1065-9. 301. Nutting C, Brada M, Brazil L, Sibtain A, Saran F, Westbury C, Moore A, Thomas DG, Traish D, Ashley S. Radiotherapy in the treatment of benign meningioma of the skull base. J Neurosurg. 1999 May; 90(5):823-7. 302. Midwinter MJ, Tytherleigh M, Ashley S. Estimation of mortality and morbidity risk in vascular surgery using POSSUM and the Portsmouth predictor equation. Br J Surg. 1999 Apr; 86(4):471-4. 303. Reber PU, Patel AG, Toyama MT, Ashley SW, Reber HA. Feline model of chronic obstructive pancreatitis: effects of acute pancreatic duct decompression on blood flow and interstitial pH. Scand J Gastroenterol. 1999 Apr; 34(4):439-44. 304. Lane JS, Whang EE, Rigberg DA, Hines OJ, Kwan D, Zinner MJ, McFadden DW, Diamond J, Ashley SW. Paracellular glucose transport plays a minor role in the unanesthetized dog. Am J Physiol. 1999 Mar; 276(3 Pt 1):G789-94. 305. Kanis JA, McCloskey EV, Powles T, Paterson AH, Ashley S, Spector T. A high incidence of vertebral fracture in women with breast cancer. Br J Cancer. 1999 Mar; 79(7-8):1179-81. 306. de Boer RH, Smith IE, Pastorino U, O'Brien ME, Ramage F, Ashley S, Goldstraw P. Pre-operative chemotherapy in early stage resectable non-small-cell lung cancer: a randomized feasibility study justifying a multicentre phase III trial. Br J Cancer. 1999 Mar; 79(9-10):1514-8. 307. Prance SE, Wilson YG, Cosgrove CM, Walker AJ, Wilkins DC, Ashley S. Ruptured abdominal aortic aneurysms: selecting patients for surgery. Eur J Vasc Endovasc Surg. 1999 Feb; 17(2):129-32. 308. Brada M, Sharpe G, Rajan B, Britton J, Wilkins PR, Guerrero D, Hines F, Traish D, Ashley S. Modifying radical radiotherapy in high grade gliomas; shortening the treatment time through acceleration. Int J Radiat Oncol Biol Phys. 1999 Jan 15; 43(2):287-92. 309. Reber PU, Lewis MP, Patel AG, Andren-Sandberg A, Ashley SW, Reber HA. Ethanol-mediated neutrophil extravasation in feline pancreas. Dig Dis Sci. 1998 Dec; 43(12):2610-5. 310. Lane JS, Kwan D, Chandler CF, Alexander P, Todd KE, McFadden DW, Ashley SW. Diverting loop versus end ileostomy during ileoanal pullthrough procedure for ulcerative colitis. Am Surg. 1998 Oct; 64(10):979-82. 311. Watson M, Duvivier V, Wade Walsh M, Ashley S, Davidson J, Papaikonomou M, Murday V, Sacks N, Eeles R. Family history of breast cancer: what do women understand and recall about their genetic risk? J Med Genet. 1998 Sep; 35(9):731-8. 312. Reber PU, Patel AG, Lewis MP, Ashley SW, Reber HA. Stenting does not decompress the pancreatic duct as effectively as surgery in experimental chronic pancreatitis. Surgery. 1998 Sep; 124(3):561-7. 313. Powles T, Eeles R, Ashley S, Easton D, Chang J, Dowsett M, Tidy A, Viggers J, Davey J. Interim analysis of the incidence of breast cancer in the Royal Marsden Hospital tamoxifen randomised chemoprevention trial. Lancet. 1998 Jul 11; 352(9122):98-101. 314. Hickish TF, Smith IE, O'Brien ME, Ashley S, Middleton G. Clinical benefit from palliative chemotherapy in non-small-cell lung cancer extends to the elderly and those with poor prognostic factors. Br J Cancer. 1998 Jul; 78(1):28-33. 315. Powles TJ, Bourne T, Athanasiou S, Chang J, Gruböck K, Ashley S, Oakes L, Tidy A, Davey J, Viggers J, Humphries S, Collins W. The effects of norethisterone on endometrial abnormalities identified by transvaginal ultrasound screening of healthy post-menopausal women on tamoxifen or placebo. Br J Cancer. 1998 Jul; 78(2):272-5. 316. Hickish TF, Smith IE, Nicolson MC, Ashley S, Priest K, Spencer L, Norman A, Middleton G, O'Brien ME. A pilot study of MVP (mitomycin-C, vinblastine and cisplatin) chemotherapy in small-cell lung cancer. Br J Cancer. 1998 Jun; 77(11):1966-70. 317. Atra A, Gerrard M, Hobson R, Imeson JD, Ashley S, Pinkerton CR. Improved cure rate in children with B-cell acute lymphoblastic leukaemia (B-ALL) and stage IV B-cell non-Hodgkin's lymphoma (B-NHL)--results of the UKCCSG 9003 protocol. Br J Cancer. 1998 Jun; 77(12):2281-5. 318. Powles TJ, McCloskey E, Paterson AH, Ashley S, Tidy VA, Nevantaus A, Rosenqvist K, Kanis J. Oral clodronate and reduction in loss of bone mineral density in women with operable primary breast cancer. J Natl Cancer Inst. 1998 May 06; 90(9):704-8. 319. Lewis MP, Reber PU, Kusske AM, Toyama MT, Todd KE, Ashley SW, Reber HA. Intragastric alcohol causes endothelin release from feline pancreas. Dig Dis Sci. 1998 May; 43(5):927-30. 320. Eisen T, Smith IE, Johnston S, Ellis PA, Prendiville J, Seymour MT, Walsh G, Ashley S. Randomized phase II trial of infusional fluorouracil, epirubicin, and cyclophosphamide versus infusional fluorouracil, epirubicin, and cisplatin in patients with advanced breast cancer. J Clin Oncol. 1998 Apr; 16(4):1350-7. 321. Brada M, Hjiyiannakis D, Hines F, Traish D, Ashley S. Short intensive primary chemotherapy and radiotherapy in sporadic primary CNS lymphoma (PCL). Int J Radiat Oncol Biol Phys. 1998 Mar 15; 40(5):1157-62. 322. Middleton GW, Smith IE, O'Brien ME, Norton A, Hickish T, Priest K, Spencer L, Ashley S. Good symptom relief with palliative MVP (mitomycin-C, vinblastine and cisplatin) chemotherapy in malignant mesothelioma. Ann Oncol. 1998 Mar; 9(3):269-73. 323. Makris A, Powles TJ, Allred DC, Ashley S, Ormerod MG, Titley JC, Dowsett M. Changes in hormone receptors and proliferation markers in tamoxifen treated breast cancer patients and the relationship with response. Breast Cancer Res Treat. 1998 Mar; 48(1):11-20. 324. Lewis MP, Reber HA, Ashley SW. Pancreatic blood flow and its role in the pathophysiology of pancreatitis. J Surg Res. 1998 Feb 15; 75(1):81-9. 325. Rigberg D, Chandler C, Ashley S, Zuckerbraun L, Thompson J. Safety of completion thyroidectomy for multicentric carcinoma. Am Surg. 1998 Feb; 64(2):189-91. 326. Ellis P, Smith I, Ashley S, Walsh G, Ebbs S, Baum M, Sacks N, McKinna J. Clinical prognostic and predictive factors for primary chemotherapy in operable breast cancer. J Clin Oncol. 1998 Jan; 16(1):107-14. 327. Gregory RK, Powles TJ, Chang JC, Ashley S. A randomised trial of six versus twelve courses of chemotherapy in metastatic carcinoma of the breast. Eur J Cancer. 1997 Nov; 33(13):2194-7. 328. Atra A, Whelan JS, Calvagna V, Shankar AG, Ashley S, Shepherd V, Souhami RL, Pinkerton CR. High-dose busulphan/melphalan with autologous stem cell rescue in Ewing's sarcoma. Bone Marrow Transplant. 1997 Nov; 20(10):843-6. 329. Wilson YG, George JK, Wilkins DC, Ashley S. Duplex assessment of run-off before femorocrural reconstruction. Br J Surg. 1997 Oct; 84(10):1360-3. 330. Todd KE, Lewis MP, Gloor B, Kusske AM, Ashley SW, Reber HA. Management decisions for unusual periampullary tumors. Am Surg. 1997 Oct; 63(10):927-32. 331. Brazil L, Thomas R, Laing R, Hines F, Guerrero D, Ashley S, Brada M. Verbally administered Barthel Index as functional assessment in brain tumour patients. J Neurooncol. 1997 Sep; 34(2):187-92. 332. Todd KE, Lewis MP, Gloor B, Lane JS, Ashley SW, Reber HA. An ETa/ETb endothelin antagonist ameliorates systemic inflammation in a murine model of acute hemorrhagic pancreatitis. Surgery. 1997 Aug; 122(2):443-9; discussion 449-50. 333. Lane JS, Todd KE, Lewis MP, Gloor B, Ashley SW, Reber HA, McFadden DW, Chandler CF. Interleukin-10 reduces the systemic inflammatory response in a murine model of intestinal ischemia/reperfusion. Surgery. 1997 Aug; 122(2):288-94. 334. Rongione AJ, Kusske AM, Ashley SW, Reber HA, McFadden DW. Interleukin-10 prevents early cytokine release in severe intraabdominal infection and sepsis. J Surg Res. 1997 Jul 01; 70(2):107-12. 335. Shankar AG, Ashley S, Radford M, Barrett A, Wright D, Pinkerton CR. Does histology influence outcome in childhood Hodgkin's disease? Results from the United Kingdom Children's Cancer Study Group. J Clin Oncol. 1997 Jul; 15(7):2622-30. 336. Whang EE, Hines OJ, Reeve JR, Grandt D, Moser JA, Bilchik AJ, Zinner MJ, McFadden DW, Ashley SW. Antisecretory mechanisms of peptide YY in rat distal colon. Dig Dis Sci. 1997 Jun; 42(6):1121-7. 337. Barquist ES, Apple SK, Jensen DM, Ashley SW. Jejunal lymphangioma. An unusual cause of chronic gastrointestinal bleeding. Dig Dis Sci. 1997 Jun; 42(6):1179-83. 338. Horwich A, Specht L, Ashley S. Survival analysis of patients with clinical stages I or II Hodgkin's disease who have relapsed after initial treatment with radiotherapy alone. Eur J Cancer. 1997 May; 33(6):848-53. 339. Liu CD, Newton TR, Zinner MJ, Ashley SW, McFadden DW. Intraluminal peptide YY induces colonic absorption in vivo. Dis Colon Rectum. 1997 Apr; 40(4):478-82. 340. Rongione AJ, Kusske AM, Kwan K, Ashley SW, Reber HA, McFadden DW. Interleukin 10 reduces the severity of acute pancreatitis in rats. Gastroenterology. 1997 Mar; 112(3):960-7. 341. Rongione AJ, Kusske AM, Reber HA, Ashley SW, McFadden DW. Interleukin-10 reduces circulating levels of serum cytokines in experimental pancreatitis. J Gastrointest Surg. 1997 Mar-Apr; 1(2):159-65; discussion 165-6. 342. Toyama MT, Patel AG, Nguyen T, Ashley SW, Reber HA. Effect of ethanol on pancreatic interstitial pH and blood flow in cats with chronic pancreatitis. Ann Surg. 1997 Feb; 225(2):223-8. 343. Thompson JE, Ashley SW. Subcapsular hematoma of the spleen associated with acute pancreatitis. Surgery. 1997 Feb; 121(2):231-3. 344. Rajan B, Ashley S, Thomas DG, Marsh H, Britton J, Brada M. Craniopharyngioma: improving outcome by early recognition and treatment of acute complications. Int J Radiat Oncol Biol Phys. 1997 Feb 01; 37(3):517-21. 345. Dunn JC, Parungo CP, Fonkalsrud EW, McFadden DW, Ashley SW. Epidermal growth factor selectively enhances functional enterocyte adaptation after massive small bowel resection. J Surg Res. 1997 Jan; 67(1):90-3. 346. Kanis JA, Powles T, Paterson AH, McCloskey EV, Ashley S. Clodronate decreases the frequency of skeletal metastases in women with breast cancer. Bone. 1996 Dec; 19(6):663-7. 347. Whang EE, Dunn JC, Mahanty H, McFadden DW, Zinner MJ, Ashley SW. Endotoxin inhibitor prevents sepsis-induced alterations in intestinal ion transport. Am J Surg. 1996 Oct; 172(4):341-4. 348. Kusske AM, Rongione AJ, Ashley SW, McFadden DW, Reber HA. Interleukin-10 prevents death in lethal necrotizing pancreatitis in mice. Surgery. 1996 Aug; 120(2):284-8; discussion 289. 349. Patel AG, McFadden DW, Hines OJ, Reber HA, Ashley SW. Palliation for pancreatic cancer. Feasibility of laparoscopic cholecystojejunostomy and gastrojejunostomy in a porcine model. Surg Endosc. 1996 Jun; 10(6):639-43. 350. Liu CD, Rongione AJ, Shin MS, Ashley SW, McFadden DW. Epidermal growth factor improves intestinal adaptation during somatostatin administration in vivo. J Surg Res. 1996 Jun; 63(1):163-8. 351. Brunicardi FC, Stagner J, Bonner-Weir S, Wayland H, Kleinman R, Livingston E, Guth P, Menger M, McCuskey R, Intaglietta M, Charles A, Ashley S, Cheung A, Ipp E, Gilman S, Howard T, Passaro E. Microcirculation of the islets of Langerhans. Long Beach Veterans Administration Regional Medical Education Center Symposium. Diabetes. 1996 Apr; 45(4):385-92. 352. Filshie J, Penn K, Ashley S, Davis CL. Acupuncture for the relief of cancer-related breathlessness. Palliat Med. 1996 Apr; 10(2):145-50. 353. Liu CD, Aloia T, Adrian TE, Newton TR, Bilchik AJ, Zinner MJ, Ashley SW, McFadden DW. Peptide YY: a potential proabsorptive hormone for the treatment of malabsorptive disorders. Am Surg. 1996 Mar; 62(3):232-6. 354. Whang EE, Dunn JC, Liu CD, Newton T, Zinner MJ, McFadden DW, Ashley SW. Amiloride inhibits meal-stimulated colonic absorption. J Surg Res. 1996 Feb 01; 60(2):303-6. 355. Liu CD, Hines OJ, Newton TR, Adrian TE, Zinner MJ, Ashley SW, McFadden DW. Cholecystokinin mediation of colonic absorption via peptide YY: foregut-hindgut axis. World J Surg. 1996 Feb; 20(2):221-7. 356. Whang EE, Dunn JC, Joffe H, Mahanty H, Zinner MJ, McFadden DW, Ashley SW. Enterocyte functional adaptation following intestinal resection. J Surg Res. 1996 Feb 01; 60(2):370-4. 357. Toyama MT, Lewis MP, Kusske AM, Reber PU, Ashley SW, Reber HA. Ischaemia-reperfusion mechanisms in acute pancreatitis. Scand J Gastroenterol Suppl. 1996; 219:20-3. 358. Powles TJ, Hickish T, Kanis JA, Tidy A, Ashley S. Effect of tamoxifen on bone mineral density measured by dual-energy x-ray absorptiometry in healthy premenopausal and postmenopausal women. J Clin Oncol. 1996 Jan; 14(1):78-84. 359. Liu CD, Rolandelli R, Ashley SW, Evans B, Shin M, McFadden DW. Laparoscopic surgery for inflammatory bowel disease. Am Surg. 1995 Dec; 61(12):1054-6. 360. Patel AG, Toyama MT, Alvarez C, Nguyen TN, Reber PU, Ashley SW, Reber HA. Pancreatic interstitial pH in human and feline chronic pancreatitis. Gastroenterology. 1995 Nov; 109(5):1639-45. 361. Reber HA, Ashley SW, McFadden D. Curative treatment for pancreatic neoplasms. Radical resection. Surg Clin North Am. 1995 Oct; 75(5):905-12. 362. Ashley SW. Sterile pancreatic necrosis: is operation necessary? J Am Coll Surg. 1995 Oct; 181(4):363-4. 363. Pendlebury S, el Awadi M, Ashley S, Brada M, Horwich A. Radiotherapy results in early stage low grade nodal non-Hodgkin's lymphoma. Radiother Oncol. 1995 Sep; 36(3):167-71. 364. Hickish TF, Smith IE, Ashley S, Middleton G. Chemotherapy for elderly patients with lung cancer. Lancet. 1995 Aug 26; 346(8974):580. 365. Patel AG, Toyama MT, Kusske AM, Alexander P, Ashley SW, Reber HA. Pylorus-preserving Whipple resection for pancreatic cancer. Is it any better? Arch Surg. 1995 Aug; 130(8):838-42; discussion 842-3. 366. Liu CD, Hines OJ, Whang EE, Balasubramaniam A, Newton TR, Zinner MJ, Ashley SW, McFadden DW. A novel synthetic analog of peptide YY, BIM-43004, given intraluminally, is proabsorptive. J Surg Res. 1995 Jul; 59(1):80-4. 367. Brada M, Thomas G, Elyan S, James N, Hines F, Ashley S, Marsh H, Bell BA, Stenning S. Improving the acceptability of high-dose radiotherapy by reducing the duration of treatment: accelerated radiotherapy in high-grade glioma. Br J Cancer. 1995 Jun; 71(6):1330-4. 368. Ellis PA, Talbot DC, Nicolson MC, Priest K, Ashley S, Smith IE. A pilot study of mitomycin, cisplatin and continuous infusion 5-fluorouracil (MCF) in advanced non-small-cell lung cancer. Br J Cancer. 1995 Jun; 71(6):1315-8. 369. Hines OJ, Bilchik AJ, McFadden DW, Rodgers PJ, Bautista N, Zinner MJ, Ashley SW. Na+/H+ exchange mediates postprandial ileal water and electrolyte transport. Dig Dis Sci. 1995 Apr; 40(4):774-80. 370. Bilchik AJ, Hines OJ, Adrian TE, Skotzko MJ, McFadden DW, Zinner MJ, Ashley SW. Early regional expression and secretion of peptide YY and enteroglucagon after massive resection of small bowel. J Am Coll Surg. 1995 Apr; 180(4):417-26. 371. Patel AG, Toyama MT, Nguyen TN, Cohen GA, Ignarro LJ, Reber HA, Ashley SW. Role of nitric oxide in the relationship of pancreatic blood flow and exocrine secretion in cats. Gastroenterology. 1995 Apr; 108(4):1215-20. 372. Thomas R, O'Connor AM, Ashley S. Speech and language disorders in patients with high grade glioma and its influence on prognosis. J Neurooncol. 1995; 23(3):265-70. 373. Liu CD, Hines OJ, Whang EE, Laird EC, Skotzko MJ, Zinner MJ, Ashley SW, McFadden DW. Pancreatic peptide YY mRNA levels increase during adaptation after small intestinal resection. J Surg Res. 1995 Jan; 58(1):6-11. 374. Hines OJ, Bilchik AJ, Ashley SW, Whang EE, Liu CD, Zinner MJ, McFadden DW. Amino acids mediate postprandial jejunal proabsorption. J Surg Res. 1995 Jan; 58(1):81-5. 375. Bilchik AJ, Hines OJ, Ashley SW, Adrian TE, Walsh J, Wong H, Liu CD, Zinner MJ, McFadden DW. Peptide YY immunoneutralization inhibits meal-induced absorption in vivo. Surgery. 1994 Dec; 116(6):1153-7; discussion 1157-8. 376. Specht L, Horwich A, Ashley S. Salvage of relapse of patients with Hodgkin's disease in clinical stages I or II who were staged with laparotomy and initially treated with radiotherapy alone. A report from the international database on Hodgkin's disease. Int J Radiat Oncol Biol Phys. 1994 Nov 15; 30(4):805-11. 377. Syndikus I, Tait D, Ashley S, Jannoun L. Long-term follow-up of young children with brain tumors after irradiation. Int J Radiat Oncol Biol Phys. 1994 Nov 15; 30(4):781-7. 378. Thomas R, James N, Guerrero D, Ashley S, Gregor A, Brada M. Hypofractionated radiotherapy as palliative treatment in poor prognosis patients with high grade glioma. Radiother Oncol. 1994 Nov; 33(2):113-6. 379. O'Brien ME, Nicolson M, Montes A, Tidy A, Ashley S, Powles TJ. Phase I study of mitozantrone, methotrexate and mitomycin with granulocyte colony-stimulating factor (filgrastim) in patients with advanced breast cancer. Br J Cancer. 1994 Nov; 70(5):980-3. 380. Alvarez C, Hunt K, Ashley SW, Reber HA. Emphysematous cholecystitis after ERCP. Dig Dis Sci. 1994 Aug; 39(8):1719-23. 381. Hines OJ, Bilchik AJ, McFadden DW, Skotzko MJ, Whang EE, Zinner MJ, Ashley SW. Up-regulation of Na+,K+ adenosine triphosphatase after massive intestinal resection. Surgery. 1994 Aug; 116(2):401-7; discussion 408. 382. Ashley S, Brooks SG, Gehani AA, Kester RC, Rees MR. Percutaneous laser recanalisation of femoropopliteal occlusions using continuous wave Nd-YAG laser and sapphire contact probe delivery system. Eur J Vasc Surg. 1994 Jul; 8(4):494-501. 383. Hines OJ, Bilchik AJ, Zinner MJ, Skotzko MJ, Moser AJ, McFadden DW, Ashley SW. Adaptation of the Na+/glucose cotransporter following intestinal resection. J Surg Res. 1994 Jul; 57(1):22-7. 384. Bilchik AJ, Hines OJ, Zinner MJ, Adrian TE, Berger JJ, Ashley SW, McFadden DW. Peptide YY augments postprandial small intestinal absorption in the conscious dog. Am J Surg. 1994 Jun; 167(6):570-4. 385. Jones AL, Smith IE, O'Brien ME, Talbot D, Walsh G, Ramage F, Robertshaw H, Ashley S. Phase II study of continuous infusion fluorouracil with epirubicin and cisplatin in patients with metastatic and locally advanced breast cancer: an active new regimen. J Clin Oncol. 1994 Jun; 12(6):1259-65. 386. Ashley SW, Schwarz M, Alvarez C, Nguyen TN, Vdovenko A, Reber HA. Pancreatic interstitial pH regulation: effects of secretory stimulation. Surgery. 1994 Apr; 115(4):503-9. 387. Ashley SW, Sherman S, Reber HA. Endoscopic measurement of pancreatic blood flow. Gastrointest Endosc Clin N Am. 1994 Apr; 4(2):369-82. 388. Hiorns LR, Nicholls J, Sloane JP, Horwich A, Ashley S, Brada M. Peripheral blood involvement in non-Hodgkin's lymphoma detected by clonal gene rearrangement as a biological prognostic marker. Br J Cancer. 1994 Feb; 69(2):347-51. 389. Rajan B, Pickuth D, Ashley S, Traish D, Monro P, Elyan S, Brada M. The management of histologically unverified presumed cerebral gliomas with radiotherapy. Int J Radiat Oncol Biol Phys. 1994 Jan 15; 28(2):405-13. 390. Rajan B, Ross G, Lim CC, Ashley S, Goode D, Traish D, Brada M. Survival in patients with recurrent glioma as a measure of treatment efficacy: prognostic factors following nitrosourea chemotherapy. Eur J Cancer. 1994; 30A(12):1809-15. 391. Bilchik AJ, Hines OJ, Adrian TE, McFadden DW, Berger JJ, Zinner MJ, Ashley SW. Peptide YY is a physiological regulator of water and electrolyte absorption in the canine small bowel in vivo. Gastroenterology. 1993 Nov; 105(5):1441-8. 392. Ashley S, Bird DL, Sugden G, Royston CM. Vertical banded gastroplasty for the treatment of morbid obesity. Br J Surg. 1993 Nov; 80(11):1421-3. 393. Ashley SW, Reber HA. Pancreatic duct permeability and pancreatitis. Pancreas. 1993 Nov; 8(6):740-1. 394. Sherman S, Alvarez C, Robert M, Ashley SW, Reber HA, Lehman GA. Polyethylene pancreatic duct stent-induced changes in the normal dog pancreas. Gastrointest Endosc. 1993 Sep-Oct; 39(5):658-64. 395. Hickish T, Roldan A, Cunningham D, Mansi J, Ashley S, Nicolson V, Gore ME, Catovsky D, Smith IE. EPIC: an effective low toxicity regimen for relapsing lymphoma. Br J Cancer. 1993 Sep; 68(3):599-604. 396. King H, Ashley S, Brathwaite D, Decayette J, Wooten DJ. Adequacy of general anesthesia for cesarean section. Anesth Analg. 1993 Jul; 77(1):84-8. 397. Brada M, Rajan B, Traish D, Ashley S, Holmes-Sellors PJ, Nussey S, Uttley D. The long-term efficacy of conservative surgery and radiotherapy in the control of pituitary adenomas. Clin Endocrinol (Oxf). 1993 Jun; 38(6):571-8. 398. Rajan B, Ashley S, Gorman C, Jose CC, Horwich A, Bloom HJ, Marsh H, Brada M. Craniopharyngioma--a long-term results following limited surgery and radiotherapy. Radiother Oncol. 1993 Jan; 26(1):1-10. 399. Huddart R, Traish D, Ashley S, Moore A, Brada M. Management of spinal astrocytoma with conservative surgery and radiotherapy. Br J Neurosurg. 1993; 7(5):473-81. 400. Alvarez C, Livingston EH, Ashley SW, Schwarz M, Reber HA. Cost-benefit analysis of the work-up for pancreatic cancer. Am J Surg. 1993 Jan; 165(1):53-8; discussion 58-60. 401. Paterson AH, Powles TJ, Kanis JA, McCloskey E, Hanson J, Ashley S. Double-blind controlled trial of oral clodronate in patients with bone metastases from breast cancer. J Clin Oncol. 1993 Jan; 11(1):59-65. 402. Paterson AH, Powles TJ, Kanis JA, McCloskey E, Hanson J, Ashley S. [Double-blind trial of oral clodronate in breast cancer patients with bone metastases]. Bull Cancer. 1993; 80(10 Suppl):50-6. 403. Bird DL, Fox JN, Ashley S, Imrie MJ. Results of the first year of breast cancer screening in a district hospital. Br J Surg. 1992 Sep; 79(9):922-4. 404. Reber HA, Karanjia ND, Alvarez C, Widdison AL, Leung FW, Ashley SW, Lutrin FJ. Pancreatic blood flow in cats with chronic pancreatitis. Gastroenterology. 1992 Aug; 103(2):652-9. 405. Soper NJ, Stockmann PT, Dunnegan DL, Ashley SW. Laparoscopic cholecystectomy. The new 'gold standard'? Arch Surg. 1992 Aug; 127(8):917-21; discussion 921-3. 406. Brada M, Ford D, Ashley S, Bliss JM, Crowley S, Mason M, Rajan B, Traish D. Risk of second brain tumour after conservative surgery and radiotherapy for pituitary adenoma. BMJ. 1992 May 23; 304(6838):1343-6. 407. Soybel DI, Ashley SW, Cheung LY. Basolateral K+ conductances in surface epithelium of Necturus antrum: effects of Ca2+ and divalent cations. Am J Physiol. 1992 Apr; 262(4 Pt 1):G651-9. 408. Brada M, Eeles R, Ashley S, Nichols J, Horwich A. Salvage radiotherapy in recurrent Hodgkin's disease. Ann Oncol. 1992 Feb; 3(2):131-5. 409. Soper NJ, Barteau JA, Clayman RV, Ashley SW, Dunnegan DL. Comparison of early postoperative results for laparoscopic versus standard open cholecystectomy. Surg Gynecol Obstet. 1992 Feb; 174(2):114-8. 410. Aliperti G, Edmundowicz SA, Soper NJ, Ashley SW. Combined endoscopic sphincterotomy and laparoscopic cholecystectomy in patients with choledocholithiasis and cholecystolithiasis. Ann Intern Med. 1991 Nov 15; 115(10):783-5. 411. Pinkerton CR, Groot-Loonen J, Barrett A, Meller ST, Tait D, Ashley S, McElwain TJ. Rapid VAC high dose melphalan regimen, a novel chemotherapy approach in childhood soft tissue sarcomas. Br J Cancer. 1991 Aug; 64(2):381-5. 412. O'Brien P, Crow J, Brada M, Ashley S, Horwich A. Hodgkin's disease of the liver; prognosis and possible indications for radiotherapy. Clin Oncol (R Coll Radiol). 1991 Jul; 3(4):189-92. 413. Jodrell DI, Smith IE, Mansi JL, Pearson MC, Walsh G, Ashley S, Sinnett HD, McKinna JA. A randomised comparative trial of mitozantrone/methotrexate/mitomycin C (MMM) and cyclophosphamide/methotrexate/5 FU (CMF) in the treatment of advanced breast cancer. Br J Cancer. 1991 May; 63(5):794-8. 414. Radford DM, Ashley SW, Wells SA, Gerhard DS. Loss of heterozygosity of markers on chromosome 11 in tumors from patients with multiple endocrine neoplasia syndrome type 1. Cancer Res. 1990 Oct 15; 50(20):6529-33. 415. Gehani AA, Sheard K, Ashley S, Brooks S, Kester RC, Rees MR. Dynamic angioplasty of total arterial occlusions. Br J Surg. 1990 Oct; 77(10):1139-41. 416. Ashley S, Sutton G, Royle G, Taylor I. A new catheter to simplify portal vein cannulation for adjuvant cytotoxic liver perfusion following resection of rectal cancer. Br J Cancer. 1990 May; 61(5):763-4. 417. Brada M, Rowley M, Grant DJ, Ashley S, Powles TJ. Hypercalcaemia in patients with disseminated breast cancer. Acta Oncol. 1990; 29(5):577-80. 418. Duchesne G, Crow J, Ashley S, Brada M, Horwich A. Changing patterns of relapse in Hodgkin's disease. Br J Cancer. 1989 Aug; 60(2):227-30. 419. Brada M, Ashley S, Nicholls J, Wist E, Colman M, McElwain TJ, Selby P, Peckham MJ, Horwich A. Stage III Hodgkin's disease--long-term results following chemotherapy, radiotherapy and combined modality therapy. Radiother Oncol. 1989 Mar; 14(3):185-98. 420. Ashley SW, Soybel DI, Moore CD, Cheung LY. Effects of aspirin and acetic acid on intracellular pH in necturus gastric mucosa. Am J Surg. 1989 Jan; 157(1):66-73. 421. Mbidde EK, Selby PJ, Perren TJ, Dearnaley DP, Whitton A, Ashley S, Workman P, Bloom HJ, McElwain TJ. High dose BCNU chemotherapy with autologous bone marrow transplantation and full dose radiotherapy for grade IV astrocytoma. Br J Cancer. 1988 Dec; 58(6):779-82. 422. Gusterson BA, Machin LG, Gullick WJ, Gibbs NM, Powles TJ, Elliott C, Ashley S, Monaghan P, Harrison S. c-erbB-2 expression in benign and malignant breast disease. Br J Cancer. 1988 Oct; 58(4):453-7. 423. Price P, Walsh G, McKinna AJ, Ashley S, Yarnold JR. Patterns of breast relapse after local excision +/- radiotherapy for early stage breast cancer. Radiother Oncol. 1988 Sep; 13(1):53-60. 424. Ashley SW, Wells SA. Tumors of the small intestine. Semin Oncol. 1988 Apr; 15(2):116-28. 425. Soybel DI, Ashley SW, Cheung LY. Effects of platelet-activating factor on canine gastric mucosal blood flow and permeability to luminal acid. Am J Surg. 1988 Jan; 155(1):180-5. 426. Soybel DI, Ashley SW, DeSchryver-Kecskemeti K, Cheung LY. Effects of luminal hyperosmolality on cellular and paracellular ion transport pathways in necturus antrum. Gastroenterology. 1987 Sep; 93(3):456-65. 427. Ashley SW, Soybel DI, Moore CD, Cheung LY. Intracellular pH (pHi) in gastric surface epithelium is more susceptible to serosal than mucosal acidification. Surgery. 1987 Aug; 102(2):371-9. 428. Cheung LY, Ashley SW. Gastric blood flow and mucosal defense mechanisms. Clin Invest Med. 1987 May; 10(3):201-8. 429. Soybel DI, Wan YL, Ashley SW, Yan ZY, Ordway FS, Cheung LY. Endoscopic measurements of canine colonic mucosal blood flow using hydrogen gas clearance. Gastroenterology. 1987 Apr; 92(4):1045-50. 430. Swarm RA, Ashley SW, Soybel DI, Ordway FS, Cheung LY. Protective effect of exogenous phospholipid on aspirin-induced gastric mucosal injury. Am J Surg. 1987 Jan; 153(1):48-53. 431. Soybel DI, Ashley SW, Swarm RA, Moore CD, Cheung LY. Effects of luminal salt concentration on electrical pathways in Necturus antrum. Am J Physiol. 1987 Jan; 252(1 Pt 1):G19-27. 432. Soybel DI, Ashley SW, Yan ZY, Swarm RA, Cheung LY. Regional gastric mucosal blood flow after parietal cell vagotomy in dogs. Surgery. 1986 Aug; 100(2):167-74. 433. Goss PE, Ashley S, Powles TJ, Coombes RC. High-dose oral medroxyprogesterone acetate in heavily pretreated patients with metastatic breast cancer. Cancer Treat Rep. 1986 Jun; 70(6):777-9. 434. Ashley SW, Soybel DI, Cheung LY. Measurements of intracellular pH in Necturus antral mucosa by microelectrode technique. Am J Physiol. 1986 May; 250(5 Pt 1):G625-32. 435. Soybel DI, Ashley SW, Yan ZY, Cheung LY. Comparison of gastric mucosal blood flow as measured by H2 gas clearance and microspheres during secretory stimulation and inhibition. Surgery. 1985 Aug; 98(2):174-82. 436. Ashley SW, Soybel DI, Cheung LY. Effect of 16,16-dimethyl prostaglandin E2 on gastric epithelial cell membrane potentials and resistances. Surgery. 1985 Aug; 98(2):166-73. 437. Ashley SW, Yan ZY, Soybel DI, Cheung LY. Endoscopic measurements of gastric mucosal blood flow in dogs. J Surg Res. 1985 May; 38(5):416-23. 438. Ashley SW, Soybel DI, De L, Cheung LY. Microelectrode studies of Necturus antral mucosa. II. Equivalent circuit analysis. Am J Physiol. 1985 May; 248(5 Pt 1):G574-9. 439. Perez DJ, Powles TJ, Smith IE, Vincent MD, Ashley S, Gordon C, Gibb J, Clarke S, Coombes RC. The modulating effects of flurbiprofen on adriamycin plus vincristine or vindesine in the treatment of advanced breast cancer. Cancer Chemother Pharmacol. 1985; 15(3):278-82. 440. Ashley SW, Sonnenschein LA, Cheung LY. Focal gastric mucosal blood flow at the site of aspirin-induced ulceration. Am J Surg. 1985 Jan; 149(1):53-9. 441. Cheung LY, De L, Ashley SW. Intracellular microelectrode studies of Necturus antral mucosa. Effect of aspirin on cell membrane potentials. Gastroenterology. 1985 Jan; 88(1 Pt 2):261-8. 442. Ashley SW, Cheung LY. New diagnostic techniques in hepatobiliary disease. Surg Annu. 1985; 17:41-67. 443. Ashley SW, Cheung LY. Measurements of gastric mucosal blood flow by hydrogen gas clearance. Am J Physiol. 1984 Oct; 247(4 Pt 1):G339-45. 444. Cheung LY, De L, Ashley SW. Effect of aspirin on epithelial cell membrane potentials of gastric fundic mucosa. Surgery. 1984 Aug; 96(2):171-8. 445. Ashley SW, Cheung LY. The SSAT-AGA (Society for Surgery of the Alimentary Tract-American Gastroenterological Association). New Orleans, May 20-23, 1984. Surg Gastroenterol. 1984; 3(2):47-53.

Send Feedback to the BWH Biomedical Research Institute.

EDIT YOUR PROFILE

Department

View all Research Faculty in the Department of Surgery

Division

View all Research Faculty: General / GI Surgery

BRI Research Center/Program Affiliation(s)

Cancer Research Center