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Kathryn M. Rexrode, MD, MPH
Associate Physician, Brigham and Women's Hospital
Associate Professor of Medicine, Harvard Medical School

Brigham and Women's Hospital
Department of Medicine
Preventive Medicine
75 Francis Street
Boston, MA 02115


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Research Narrative:

Dr. Rexrode examines risk factors for heart disease and stroke in women. She has a particular interest in the role of metabolic and hormonal factors, as well as understanding sex differences. She has studied the effects of endogenous sex hormones, such as estrogen and testosterone, and related genetic variants, and risk of cardiovascular disease. She is Principal Investigator of  several NIH grants examining risk factors for ischemic stroke and coronary heart disease in women. She also leads two studies examining factors that might modify mammographic density and breast outcomes. She is actively involved in several large studies of women's health, including the Nurses' Health Study, the Kronos Early Estrogen Prevention Study, and the Women's Health Initiative.


Education:
Harvard School of Public Health , 1996, MPH
Case Western Reserve U. School of Medicine , 1991, MD

Publications (Pulled from Harvard Catalyst Profiles):

1. Yu B, Zanetti KA, Temprosa M, Albanes D, Appel N, Barrera CB, Ben-Shlomo Y, Boerwinkle E, Casas JP, Clish C, Dale C, Dehghan A, Derkach A, Eliassen AH, Elliott P, Fahy E, Gieger C, Gunter MJ, Harada S, Harris T, Herr DR, Herrington D, Hirschhorn JN, Hoover E, Hsing AW, Johansson M, Kelly RS, Khoo CM, Kivimäki M, Kristal BS, Langenberg C, Lasky-Su J, Lawlor DA, Lotta LA, Mangino M, Le Marchand L, Mathé E, Matthews CE, Menni C, Mucci LA, Murphy R, Oresic M, Orwoll E, Ose J, Pereira AC, Playdon MC, Poston L, Price J, Qi Q, Rexrode K, Risch A, Sampson J, Seow WJ, Sesso HD, Shah SH, Shu XO, Smith GCS, Sovio U, Stevens VL, Stolzenberg-Solomon R, Takebayashi T, Tillin T, Travis R, Tzoulaki I, Ulrich CM, Vasan RS, Verma M, Wang Y, Wareham NJ, Wong A, Younes N, Zhao H, Zheng W, Moore SC. The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies. Am J Epidemiol. 2019 Jun 01; 188(6):991-1012.

2. Hu J, Li Y, Zhang B, Zheng T, Li J, Peng Y, Zhou A, Buka SL, Liu S, Zhang Y, Shi K, Xia W, Rexrode K, Xu S. Impact of the 2017 ACC/AHA Guideline for High Blood Pressure on Evaluating Gestational Hypertension Associated Risks for Newborns and Mothers: A Retrospective Birth Cohort Study. Circ Res. 2019 May 20.

3. Kachalia A, Sivashanker K, Rexrode K, Nour N. Healthcare portraiture and unconscious bias. BMJ. 2019 Apr 12; 365:l1668.

4. Rist PM, Buring JE, Ridker PM, Kase CS, Kurth T, Rexrode KM. Lipid levels and the risk of hemorrhagic stroke among women. Neurology. 2019 May 07; 92(19):e2286-e2294.

5. Jiménez MC, Manson JE, Cook NR, Kawachi I, Wassertheil-Smoller S, Haring B, Nassir R, Rhee JJ, Sealy-Jefferson S, Rexrode KM. Racial Variation in Stroke Risk Among Women by Stroke Risk Factors. Stroke. 2019 Apr; 50(4):797-804.

6. Liu G, Guasch-Ferré M, Hu Y, Li Y, Hu FB, Rimm EB, Manson JE, Rexrode KM, Sun Q. Nut Consumption in Relation to Cardiovascular Disease Incidence and Mortality Among Patients With Diabetes Mellitus. Circ Res. 2019 Mar 15; 124(6):920-929.

7. Xu H, Qian J, Paynter NP, Zhang X, Whitcomb BW, Tworoger SS, Rexrode KM, Hankinson SE, Balasubramanian R. Estimating the receiver operating characteristic curve in matched case control studies. Stat Med. 2019 Feb 10; 38(3):437-451.

8. Huang T, Zeleznik OA, Poole EM, Clish CB, Deik AA, Scott JM, Vetter C, Schernhammer ES, Brunner R, Hale L, Manson JE, Hu FB, Redline S, Tworoger SS, Rexrode KM. Habitual sleep quality, plasma metabolites and risk of coronary heart disease in post-menopausal women. Int J Epidemiol. 2018 Oct 26.

9. Stuart JJ, Tanz LJ, Cook NR, Spiegelman D, Missmer SA, Rimm EB, Rexrode KM, Mukamal KJ, Rich-Edwards JW. Hypertensive Disorders of Pregnancy and 10-Year Cardiovascular Risk Prediction. J Am Coll Cardiol. 2018 Sep 11; 72(11):1252-1263.

10. Demel SL, Rexrode KM. Response by Demel and Rexrode to Letter Regarding Article, "Stroke Risk Factors Unique to Women". Stroke. 2018 Sep; 49(9):e291.