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Kathryn M. Rexrode, MD, MPH
Associate Physician, Brigham and Women's Hospital
Associate Professor of Medicine, Harvard Medical School

Brigham and Women's Hospital
Department of Medicine
Preventive Medicine
75 Francis Street
Boston, MA 02115

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Research Narrative:

Dr. Rexrode examines risk factors for heart disease and stroke in women. She has a particular interest in the role of metabolic and hormonal factors, as well as understanding sex differences. She has studied the effects of endogenous sex hormones, such as estrogen and testosterone, and related genetic variants, and risk of cardiovascular disease. She is Principal Investigator of  several NIH grants examining risk factors for ischemic stroke and coronary heart disease in women. She also leads two studies examining factors that might modify mammographic density and breast outcomes. She is actively involved in several large studies of women's health, including the Nurses' Health Study, the Kronos Early Estrogen Prevention Study, and the Women's Health Initiative.

Harvard School of Public Health , 1996, MPH
Case Western Reserve U. School of Medicine , 1991, MD

Publications (Pulled from Harvard Catalyst Profiles):

1. Jiménez MC, Manson JE, Cook NR, Kawachi I, Wassertheil-Smoller S, Haring B, Nassir R, Rhee JJ, Sealy-Jefferson S, Rexrode KM. Racial Variation in Stroke Risk Among Women by Stroke Risk Factors. Stroke. 2019 Apr; 50(4):797-804.

2. Liu G, Guasch-Ferré M, Hu Y, Li Y, Hu FB, Rimm EB, Manson JE, Rexrode KM, Sun Q. Nut Consumption in Relation to Cardiovascular Disease Incidence and Mortality Among Patients With Diabetes Mellitus. Circ Res. 2019 Mar 15; 124(6):920-929.

3. Xu H, Qian J, Paynter NP, Zhang X, Whitcomb BW, Tworoger SS, Rexrode KM, Hankinson SE, Balasubramanian R. Estimating the receiver operating characteristic curve in matched case control studies. Stat Med. 2019 Feb 10; 38(3):437-451.

4. Huang T, Zeleznik OA, Poole EM, Clish CB, Deik AA, Scott JM, Vetter C, Schernhammer ES, Brunner R, Hale L, Manson JE, Hu FB, Redline S, Tworoger SS, Rexrode KM. Habitual sleep quality, plasma metabolites and risk of coronary heart disease in post-menopausal women. Int J Epidemiol. 2018 Oct 26.

5. Stuart JJ, Tanz LJ, Cook NR, Spiegelman D, Missmer SA, Rimm EB, Rexrode KM, Mukamal KJ, Rich-Edwards JW. Hypertensive Disorders of Pregnancy and 10-Year Cardiovascular Risk Prediction. J Am Coll Cardiol. 2018 Sep 11; 72(11):1252-1263.

6. Demel SL, Rexrode KM. Response by Demel and Rexrode to Letter Regarding Article, "Stroke Risk Factors Unique to Women". Stroke. 2018 Sep; 49(9):e291.

7. Ma L, Liu G, Zong G, Sampson L, Hu FB, Willett WC, Rimm EB, Manson JE, Rexrode KM, Sun Q. Intake of glucosinolates and risk of coronary heart disease in three large prospective cohorts of US men and women. Clin Epidemiol. 2018; 10:749-762.

8. Liu G, Li Y, Hu Y, Zong G, Li S, Rimm EB, Hu FB, Manson JE, Rexrode KM, Shin HJ, Sun Q. Influence of Lifestyle on Incident Cardiovascular Disease and Mortality in Patients With Diabetes Mellitus. J Am Coll Cardiol. 2018 Jun 26; 71(25):2867-2876.

9. Zheng Y, Xu M, Heianza Y, Ma W, Wang T, Sun D, Albert CM, Hu FB, Rexrode KM, Manson JE, Qi L. Gallstone disease and increased risk of mortality: Two large prospective studies in US men and women. J Gastroenterol Hepatol. 2018 Nov; 33(11):1925-1931.

10. Tabung FK, Giovannucci EL, Giulianini F, Liang L, Chandler PD, Balasubramanian R, Manson JE, Cespedes Feliciano EM, Hayden KM, Van Horn L, Rexrode KM. An Empirical Dietary Inflammatory Pattern Score Is Associated with Circulating Inflammatory Biomarkers in a Multi-Ethnic Population of Postmenopausal Women in the United States. J Nutr. 2018 Apr 20.