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Kathryn M. Rexrode, MD, MPH
Associate Physician, Brigham and Women's Hospital
Associate Professor of Medicine, Harvard Medical School

Brigham and Women's Hospital
Department of Medicine
Preventive Medicine
75 Francis Street
Boston, MA 02115

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Research Narrative:

Dr. Rexrode examines risk factors for heart disease and stroke in women. She has a particular interest in the role of metabolic and hormonal factors, as well as understanding sex differences. She has studied the effects of endogenous sex hormones, such as estrogen and testosterone, and related genetic variants, and risk of cardiovascular disease. She is Principal Investigator of  several NIH grants examining risk factors for ischemic stroke and coronary heart disease in women. She also leads two studies examining factors that might modify mammographic density and breast outcomes. She is actively involved in several large studies of women's health, including the Nurses' Health Study, the Kronos Early Estrogen Prevention Study, and the Women's Health Initiative.

Harvard School of Public Health , 1996, MPH
Case Western Reserve U. School of Medicine , 1991, MD

Publications (Pulled from Harvard Catalyst Profiles):

1. Rist PM, Buring JE, Rexrode KM, Cook NR, Rost NS. Prospectively collected lifestyle and health information as risk factors for white matter hyperintensity volume in stroke patients. Eur J Epidemiol. 2019 Aug 09.

2. Ding M, Zeleznik OA, Guasch-Ferre M, Hu J, Lasky-Su J, Lee IM, Jackson RD, Shadyab AH, LaMonte MJ, Clish C, Eliassen AH, Sacks F, Willett WC, Hu FB, Rexrode KM, Kraft P. Metabolome-wide Association Study with Habitual Physical Activity in Four Prospective Cohort Studies. Am J Epidemiol. 2019 Jul 31.

3. Traylor M, Anderson CD, Rutten-Jacobs LCA, Falcone GJ, Comeau ME, Ay H, Sudlow CLM, Xu H, Mitchell BD, Cole JW, Rexrode K, Jimenez-Conde J, Schmidt R, Grewal RP, Sacco R, Ribases M, Rundek T, Rosand J, Dichgans M, Lee JM, Langefeld CD, Kittner SJ, Markus HS, Woo D, Malik R. Subtype Specificity of Genetic Loci Associated With Stroke in 16?664 Cases and 32?792 Controls. Circ Genom Precis Med. 2019 Jul; 12(7):e002338.

4. Jiao J, Liu G, Shin HJ, Hu FB, Rimm EB, Rexrode KM, Manson JE, Zong G, Sun Q. Dietary fats and mortality among patients with type 2 diabetes: analysis in two population based cohort studies. BMJ. 2019 07 02; 366:l4009.

5. Tabung FK, Balasubramanian R, Liang L, Clinton SK, Cespedes Feliciano EM, Manson JE, Van Horn L, Wactawski-Wende J, Clish CB, Giovannucci EL, Rexrode KM. Identifying Metabolomic Profiles of Insulinemic Dietary Patterns. Metabolites. 2019 Jun 24; 9(6).

6. Tabung FK, Liang L, Huang T, Balasubramanian R, Zhao Y, Chandler PD, Manson JE, Cespedes Feliciano EM, Hayden KM, Van Horn L, Clish CB, Giovannucci EL, Rexrode KM. Identifying metabolomic profiles of inflammatory diets in postmenopausal women. Clin Nutr. 2019 Jun 17.

7. Tabung F, Balasubramanian R, Clinton S, Liang L, Clish C, Giovannucci E, Rexrode K. Identifying Metabolomic Profiles of Insulinemic Dietary Patterns (OR31-03-19). Curr Dev Nutr. 2019 Jun; 3(Suppl 1).

8. Liu X, Guasch-Ferré M, Drouin-Chartier JP, Tobias D, Bhupathiraju S, Rexrode K, Sun Q, Li Y. Increased Nut Consumption and Subsequent Cardiovascular Disease Risk Among U.S. Men and Women: Three Large Prospective Cohort Studies (OR17-08-19). Curr Dev Nutr. 2019 Jun; 3(Suppl 1).

9. Yu B, Zanetti KA, Temprosa M, Albanes D, Appel N, Barrera CB, Ben-Shlomo Y, Boerwinkle E, Casas JP, Clish C, Dale C, Dehghan A, Derkach A, Eliassen AH, Elliott P, Fahy E, Gieger C, Gunter MJ, Harada S, Harris T, Herr DR, Herrington D, Hirschhorn JN, Hoover E, Hsing AW, Johansson M, Kelly RS, Khoo CM, Kivimäki M, Kristal BS, Langenberg C, Lasky-Su J, Lawlor DA, Lotta LA, Mangino M, Le Marchand L, Mathé E, Matthews CE, Menni C, Mucci LA, Murphy R, Oresic M, Orwoll E, Ose J, Pereira AC, Playdon MC, Poston L, Price J, Qi Q, Rexrode K, Risch A, Sampson J, Seow WJ, Sesso HD, Shah SH, Shu XO, Smith GCS, Sovio U, Stevens VL, Stolzenberg-Solomon R, Takebayashi T, Tillin T, Travis R, Tzoulaki I, Ulrich CM, Vasan RS, Verma M, Wang Y, Wareham NJ, Wong A, Younes N, Zhao H, Zheng W, Moore SC. The Consortium of Metabolomics Studies (COMETS): Metabolomics in 47 Prospective Cohort Studies. Am J Epidemiol. 2019 Jun 01; 188(6):991-1012.

10. Hu J, Li Y, Zhang B, Zheng T, Li J, Peng Y, Zhou A, Buka SL, Liu S, Zhang Y, Shi K, Xia W, Rexrode KM, Xu S. Impact of the 2017 ACC/AHA Guideline for High Blood Pressure on Evaluating Gestational Hypertension-Associated Risks for Newborns and Mothers. Circ Res. 2019 Jul 05; 125(2):184-194.