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Raouf Khalil, PhD
Associate Research Associate, Brigham and Women's Hospital
Associate Professor of Surgery, Harvard Medical School

Brigham and Women's Hospital
Department of Surgery
75 Francis Street
Boston, MA 02115


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Education:
PhD

Publications (Pulled from Harvard Catalyst Profiles):

1. Yu W, Gao W, Rong D, Wu Z, Khalil RA. Molecular determinants of microvascular dysfunction in hypertensive pregnancy and preeclampsia. Microcirculation. 2018 Oct 19; e12508.

2. Ren Z, Cui N, Zhu M, Khalil RA. Placental growth factor reverses decreased vascular and uteroplacental MMP-2 and MMP-9 and increased MMP-1 and MMP-7 and collagen types I and IV in hypertensive pregnancy. Am J Physiol Heart Circ Physiol. 2018 Jul 01; 315(1):H33-H47.

3. Yin Z, He W, Li Y, Li D, Li H, Yang Y, Wei Z, Shen B, Wang X, Cao Y, Khalil RA. Adaptive reduction of human myometrium contractile activity in response to prolonged uterine stretch during term and twin pregnancy. Role of TREK-1 channel. Biochem Pharmacol. 2018 06; 152:252-263.

4. Liu Z, Khalil RA. Evolving mechanisms of vascular smooth muscle contraction highlight key targets in vascular disease. Biochem Pharmacol. 2018 07; 153:91-122.

5. Khalil RA. Preface. Adv Pharmacol. 2018; 81:xi-xii.

6. Yin Z, Li Y, He W, Li D, Li H, Yang Y, Shen B, Wang X, Cao Y, Khalil RA. Progesterone inhibits contraction and increases TREK-1 potassium channel expression in late pregnant rat uterus. Oncotarget. 2018 Jan 02; 9(1):651-661.

7. Christou H, Hudalla H, Michael Z, Filatava EJ, Li J, Zhu M, Possomato-Vieira JS, Dias-Junior C, Kourembanas S, Khalil RA. Impaired Pulmonary Arterial Vasoconstriction and Nitric Oxide-Mediated Relaxation Underlie Severe Pulmonary Hypertension in the Sugen-Hypoxia Rat Model. J Pharmacol Exp Ther. 2018 Feb; 364(2):258-274.

8. Liu J, Jia X, Jia S, Qin X, Zhang T, Liu L, Li H, Rong D, Zhou Z, Song Y, Zuo S, Duan C, Wu Z, Wei R, Ge Y, Wang X, Kong W, Xu X, Khalil RA, Huo Y, Guo W. Small infrarenal aortic diameter associated with lower-extremity peripheral artery disease in Chinese hypertensive adults. Sci Rep. 2017 Nov 06; 7(1):14547.

9. Wang X, Khalil RA. Matrix Metalloproteinases, Vascular Remodeling, and Vascular Disease. Adv Pharmacol. 2018; 81:241-330.

10. Dias-Junior CA, Chen J, Cui N, Chiang CL, Zhu M, Ren Z, Possomato-Vieira JS, Khalil RA. Angiogenic imbalance and diminished matrix metalloproteinase-2 and -9 underlie regional decreases in uteroplacental vascularization and feto-placental growth in hypertensive pregnancy. Biochem Pharmacol. 2017 12 15; 146:101-116.