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Charles Lee, PhD
Cytogeneticist, Brigham and Women's Hospital
Associate Professor of Pathology, Harvard Medical School
Fellow of the American College of Medical Genetics

Brigham and Women's Hospital
Department of Pathology
Division of Cytogenetics
75 Francis Street
Boston, MA 02115

Research Location: Eugene Braunwald Research Center

Research Email: clee@rics.bwh.harvard.edu

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Research Narrative:

Dr. Charles Lee is the Director of the Molecular Genetic Research Unit and the Cytogenetics Core for the Harvard Cancer Center, an Associate Professor at Harvard Medical School, and a Board-certified Clinical Cytogeneticist at Brigham and Women’s Hospital. Dr. Lee is also cross appointed as an Associate Member of the Broad Institute and holds an honorary Full Professorship at the Chinese University of Hong Kong. He has been named a Fellow of the American Association for the Advancement of Science (AAAS).

 
Dr. Lee received his doctoral degree from the University of Alberta, Canada in 1996 and was subsequently an NSERC research fellow at the University of Cambridge, UK from 1996-1998. He then completed his Clinical Cytogenetics fellowship at Harvard Medical School, USA from 1998-2001, and became board certified by the American Board of Medical Genetics in 2002 in Clinical Cytogenetics. Dr. Lee is the principal investigator on grants from the National Cancer Institute, the National Human Genome Research Institute, and the National Institute of General Medicine. He has authored / coauthored over 135 publications in top journals such as Nature, Science, Cell, Proceedings of the National Academy of Sciences USA, and Nature Genetics. He co-chairs the structural variation analysis group for the International 1000 Genomes Project, is a regular grant reviewer for the Genes, Health and Development Study Section at the National Institutes of Health, and formerly an Associate Editor for the American Journal of Human Genetics. He also serves on advisory committees for the International Standard Cytogenomic Array (ISCA) Consortium, the Cancer Cytogenomics Microarray Consortium (CCMC), the NIH-sponsored prenatal microarray study and the US Food and Drug Administration (FDA).
 
Among Dr. Lee's accolades, he received a Ph.D. studentship from the Alberta Heritage Foundation for Medical Research (1994-96), postdoctoral fellowship awards from both the Medical Research Council of Canada (1996) and the Natural Sciences and Engineering Research Council of Canada (1996-98), a scientific Team Award from the American Association for Cancer Research (2007), the C. Thomas Caskey lectureship from the University of South Carolina (2008), the George Brumley Jr. Memorial Award from Duke University (2010), the Vandenberge Chair Award from the Center for Human Genetics - Katholic University of Leuven in Belgium (2012) and the Chen Global Investigator Award from the Human Genome Organization (2012).
 
In 2008, at the age of 39, Dr. Lee became the youngest recipient of the Ho-Am Prize in Medicine (also referred to as the "Korean Nobel Prize") for his 2004 discovery of widespread structural genomic variation in the human genome and his seminal contributions to this new field of human genetics ever since.
 

 


Education:
University of Alberta, 1996, PhD
PhD

Honors/Awards:
2007 - Scientific Team Award, American Association for Cancer Research (AACR)
2008 - C. Thomas Caskey lectureship, University of South Carolina
2008 - Ho-Am Prize in Medicine, Ho-Am Foundation, South Korea
2010 - George Brumley Jr. Memorial Award, Duke University
2012 - The Vandenberge Chair Award, Katholic University of Leuven, Belgium
2012 - Chen Global Investigator Award, Human Genome Organization (HUGO)
2012 - Fellow, American Association for the Advancement of Science (AAAS)

Lab Members:
Sunita Setlur, PhD, Instructor in Pathology
Han Soo Park, MD, PhD, Postdoctoral Fellow
Chengsheng Zhang, MD, PhD, Research Associate
Marcin von Grotthus, PhD, Bioinformatician
Rebecca Iskow, PhD, Postdoctoral Fellow
Upeka Samarakoon, PhD, Postdoctoral Fellow
Kun Woo Kim, MD, PhD, Postdoctoral Fellow
Qihui Zhu, PhD, Postdoctoral Fellow
Katayoon Darvishi, PhD, Research Associate
Omer Gokcumen, PhD, Postdoctoral Fellow