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Ronald L. Neppl, PhD
Assistant Professor, Harvard Medical School

Brigham and Women's Hospital
Department of Orthopedic Surgery
75 Francis Street
Boston, MA 02115


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Research Narrative:

The Neppl laboratory is focused on the molecular regulation of skeletal muscle homeostasis in health and disease. Our overarching goal is to understand how long non-coding RNAs (lncRNAs) control the essential processes of myogenesis and hypertrophic growth, and how perturbations in these processes may lead to a disease state resulting in muscle atrophy. Using traditional biochemical and molecular biology techniques, in vivo and in vitro model systems, as well as next generation RNA sequencing, we seek to discover and understand the biological roles these lncRNAs play in the maintenance of lean muscle mass.


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