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Michelle Holmes, DR.P.H

Brigham and Women's Hospital
Department of Medicine
Channing Division of Network Medicine
75 Francis Street
Boston, MA 02115

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Research Narrative:

I am an associate professor of medicine at Harvard Medical School and an associate
professor in the department of Epidemiology at Harvard School of Public Health. My
research interests include lifestyle factors (diet, weight change, physical activity, and
psychosocial factors, common medications) affecting quality of life and survival after
a breast cancer diagnosis, as well as the association between diet and breast cancer
risk. Other research interests include diet and lifestyle influences on endogenous levels
of steroid hormones and insulin-like growth factors, and ethnic differences in obesity
and other lifestyle factors affecting chronic disease risk. I have worked with the Nurses’
Health Study since 1997.

I am the co-creator and co-Principal Investigator of the Africa/HSPH Partnership for
Cohort Research and Training (PaCT) project. In this ambitious project modeled after
Harvard’s Cohort studies, we plan to enroll 500,000 participants (60% women) across
Nigeria, South Africa, Uganda, Tanzania to study and prevent the chronic disease
tsunami (high blood pressure, cancer, diabetes) about to overwhelm HIV, TB, and
malaria in Africa. I have recruited collaborative teams of 5-7 people at each of 5 African
centers of excellence and organized pilot studies at each site. I have organized 4 all-
collaborator meetings, in South Africa, Tanzania, Greece, and Sweden. I have also
organized 2 global integration meetings with similar cohorts from Mexico, India, and
Sweden held in Hydra Greece 2010 and Sigtuna Sweden 2012