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Yanmei Tie, PhD
Neuroscientist, Brigham and Women's Hospital
Assistant Professor of Neurosurgery, Harvard Medical School

Brigham and Women's Hospital
Department of Neurosurgery
75 Francis Street
Boston, MA 02115


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Research Narrative:

Dr. Tie received her Ph.D. in Biomedical Engineering and M.S. in Electrical Engineering from Louisiana Tech University. Her research focuses on improving presurgical brain mapping by developing and applying advanced neuroimaging techniques, such as functional magnetic resonance imaging (fMRI) and diffusion MRI. In addition to the conventional task-based fMRI for mapping motor and language functions, Dr. Tie has developed easy-to-perform resting-state and movie-watching fMRI paradigms for those patients who cannot perform tasks due to neurological deficits. Dr. Tie is also interested in combining functional and structural brain connectivity to understand neural mechanism of disease pathophysiology as well as treatment-induced cognitive impairments in patients with neurological disorders. The goals are to inform therapeutic development and improve patients’ overall well-being.

Golby Lab


Education:
Louisiana Tech University, 2005, PhD
Louisiana Tech University, 2005, MS

Additional News:



Publications (Pulled from Harvard Catalyst Profiles):

1. Unadkat P, Fumagalli L, Rigolo L, Vangel MG, Young GS, Huang R, Mukundan S, Golby A, Tie Y. Functional MRI Task Comparison for Language Mapping in Neurosurgical Patients. J Neuroimaging. 2019 May; 29(3):348-356.

2. Silva MA, See AP, Essayed WI, Golby AJ, Tie Y. Challenges and techniques for presurgical brain mapping with functional MRI. Neuroimage Clin. 2018; 17:794-803.

3. Chen Z, Tie Y, Olubiyi O, Zhang F, Mehrtash A, Rigolo L, Kahali P, Norton I, Pasternak O, Rathi Y, Golby AJ, O'Donnell LJ. Corticospinal tract modeling for neurosurgical planning by tracking through regions of peritumoral edema and crossing fibers using two-tensor unscented Kalman filter tractography. Int J Comput Assist Radiol Surg. 2016 Aug; 11(8):1475-86.

4. Geddes MR, Tie Y, Gabrieli JD, McGinnis SM, Golby AJ, Whitfield-Gabrieli S. Altered functional connectivity in lesional peduncular hallucinosis with REM sleep behavior disorder. Cortex. 2016 Jan; 74:96-106.

5. Tie Y, Rigolo L, Ozdemir Ovalioglu A, Olubiyi O, Doolin KL, Mukundan S, Golby AJ. A New Paradigm for Individual Subject Language Mapping: Movie-Watching fMRI. J Neuroimaging. 2015 Sep-Oct; 25(5):710-20.

6. Olubiyi OI, Ozdemir A, Incekara F, Tie Y, Dolati P, Hsu L, Santagata S, Chen Z, Rigolo L, Golby AJ. Intraoperative Magnetic Resonance Imaging in Intracranial Glioma Resection: A Single-Center, Retrospective Blinded Volumetric Study. World Neurosurg. 2015 Aug; 84(2):528-36.

7. Chen Z, Tie Y, Olubiyi O, Rigolo L, Mehrtash A, Norton I, Pasternak O, Rathi Y, Golby AJ, O'Donnell LJ. Reconstruction of the arcuate fasciculus for surgical planning in the setting of peritumoral edema using two-tensor unscented Kalman filter tractography. Neuroimage Clin. 2015; 7:815-22.

8. Radmanesh A, Zamani AA, Whalen S, Tie Y, Suarez RO, Golby AJ. Comparison of seeding methods for visualization of the corticospinal tracts using single tensor tractography. Clin Neurol Neurosurg. 2015 Feb; 129:44-9.

9. Langs G, Sweet A, Lashkari D, Tie Y, Rigolo L, Golby AJ, Golland P. Decoupling function and anatomy in atlases of functional connectivity patterns: language mapping in tumor patients. Neuroimage. 2014 Dec; 103:462-475.

10. Tie Y, Rigolo L, Norton IH, Huang RY, Wu W, Orringer D, Mukundan S, Golby AJ. Defining language networks from resting-state fMRI for surgical planning--a feasibility study. Hum Brain Mapp. 2014 Mar; 35(3):1018-30.