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Yanmei Tie, PhD
Neuroscientist, Brigham and Women's Hospital
Assistant Professor of Neurosurgery, Harvard Medical School

Brigham and Women's Hospital
Department of Neurosurgery
75 Francis Street
Boston, MA 02115


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Research Narrative:

I am an Assistant Professor of Neurosurgery at BWH and HMS. My research endeavors focus on developing and applying advanced signal and image processing techniques to multiple brain mapping modalities, particularly functional magnetic resonance imaging (fMRI) and diffusion tensor imaging (DTI), in order to improve pre-surgical planning for neurosurgical patients. I have extensive experience in fMRI paradigm development and data analysis, as well as clinical utility studies for evaluation of brain mapping techniques. I have also led the effort of developing resting-state and movie-watching fMRI paradigms for the patients who cannot perform task-based fMRI due to language or other neurologic deficits. My research interests also include using resting-state fMRI to study neural mechanism and develop neuroimaging biomarkers for a variety of neurological disorders.


Education:
PhD

Publications (Pulled from Harvard Catalyst Profiles):

1. Unadkat P, Fumagalli L, Rigolo L, Vangel MG, Young GS, Huang R, Mukundan S, Golby A, Tie Y. Functional MRI Task Comparison for Language Mapping in Neurosurgical Patients. J Neuroimaging. 2019 May; 29(3):348-356.

2. Silva MA, See AP, Essayed WI, Golby AJ, Tie Y. Challenges and techniques for presurgical brain mapping with functional MRI. Neuroimage Clin. 2018; 17:794-803.

3. Chen Z, Tie Y, Olubiyi O, Zhang F, Mehrtash A, Rigolo L, Kahali P, Norton I, Pasternak O, Rathi Y, Golby AJ, O'Donnell LJ. Corticospinal tract modeling for neurosurgical planning by tracking through regions of peritumoral edema and crossing fibers using two-tensor unscented Kalman filter tractography. Int J Comput Assist Radiol Surg. 2016 Aug; 11(8):1475-86.

4. Geddes MR, Tie Y, Gabrieli JD, McGinnis SM, Golby AJ, Whitfield-Gabrieli S. Altered functional connectivity in lesional peduncular hallucinosis with REM sleep behavior disorder. Cortex. 2016 Jan; 74:96-106.

5. Tie Y, Rigolo L, Ozdemir Ovalioglu A, Olubiyi O, Doolin KL, Mukundan S, Golby AJ. A New Paradigm for Individual Subject Language Mapping: Movie-Watching fMRI. J Neuroimaging. 2015 Sep-Oct; 25(5):710-20.

6. Olubiyi OI, Ozdemir A, Incekara F, Tie Y, Dolati P, Hsu L, Santagata S, Chen Z, Rigolo L, Golby AJ. Intraoperative Magnetic Resonance Imaging in Intracranial Glioma Resection: A Single-Center, Retrospective Blinded Volumetric Study. World Neurosurg. 2015 Aug; 84(2):528-36.

7. Chen Z, Tie Y, Olubiyi O, Rigolo L, Mehrtash A, Norton I, Pasternak O, Rathi Y, Golby AJ, O'Donnell LJ. Reconstruction of the arcuate fasciculus for surgical planning in the setting of peritumoral edema using two-tensor unscented Kalman filter tractography. Neuroimage Clin. 2015; 7:815-22.

8. Radmanesh A, Zamani AA, Whalen S, Tie Y, Suarez RO, Golby AJ. Comparison of seeding methods for visualization of the corticospinal tracts using single tensor tractography. Clin Neurol Neurosurg. 2015 Feb; 129:44-9.

9. Langs G, Sweet A, Lashkari D, Tie Y, Rigolo L, Golby AJ, Golland P. Decoupling function and anatomy in atlases of functional connectivity patterns: language mapping in tumor patients. Neuroimage. 2014 Dec; 103:462-475.

10. Tie Y, Rigolo L, Norton IH, Huang RY, Wu W, Orringer D, Mukundan S, Golby AJ. Defining language networks from resting-state fMRI for surgical planning--a feasibility study. Hum Brain Mapp. 2014 Mar; 35(3):1018-30.