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Helen A. Christou, MD
Associate Chair for Research, Brigham and Women's Hospital
Associate Professor of Pediatrics, Harvard Medical School

Brigham and Women's Hospital
Department of Newborn Medicine
75 Francis Street
Boston, MA 02115

Research Location: Thorn Research Building

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Research Narrative:

Research at the Christou Lab is driven by our desire to improve the quality of life of ill infants, premature and full term, through discovery and translation. Dr. Christou is a clinically active academic neonatologist caring for infants in the Neonatal Intensive Care Unit (NICU) and directing her research laboratory at the Thorn Research Building of Brigham and Women's Hospital. We bring clinically relevant questions from the NICU to the research laboratory and innovative intervention. Our research efforts are focused on Pulmonary Hypertension, a disease of full term and premature infants, children, and adults and on Bronchopulmonary Dysplasia, the most common long term complication of premature birth. Using preclinical models and translational approaches we seek to understand the factors contributing to these diseases and develop novel ways to treat them. Current projects include: 1) Study of beneficial effects of carbonic anhydrase inhibition in preclinical models of Pulmonary Hypertension 2) Study of the impact of clinical interventions in respiratory outcomes in preterm infants 3) Study of the importance of cord blood biomarkers associated with fetal growth patterns in common morbidities of adult onset.