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Michael Elliott Weinblatt, m.d.
Senior Physician, Brigham and Women's Hospital
John R. Riedman Professor of Medicine, Harvard Medical School

Brigham and Women's Hospital
Department of Medicine
Rheumatology, Immunology
75 Francis Street
Boston, MA 02115


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Research Narrative:

 My major interest is therapeutics in rheumatoid arthritis. I directed a research team that was involved in the first studies of methotrexate in rheumatoid arthritis as well as most the biologics used in rheumatoid arthritis. I currently co-direct a large patient registry in rheumatoid arthritis called BRASS.


Education:
university of maryland school of medicine, 1975, md

Honors/Awards:
american colllege of rheumatology presidential gold medal
american college of rheumatology distinquished clinical investigator
fellow royal college of physicians united kingdom
master american college of rheumatology
Carol Nachman Award for Rheumatology (Germany)
John R. and Eileen K. Riedman Profesor of Medicine, Harvard Medical School
The R. Bruce and Joan M. Mickey Distinguished Chair in Rheumatology, Brigham and Women’s Hospital

Publications (Pulled from Harvard Catalyst Profiles):

1. Winthrop KL, Weinblatt ME, Crow MK, Burmester GR, Mease PJ, So AK, Bykerk V, Van Vollenhoven RF, Dougados M, Kay J, Mariette X, Sieper J, Melchers F, Cronstein BN, Shevach E, Breedfeld FC, Kalden J, Smolen JS, Furst DE. Unmet need in rheumatology: reports from the Targeted Therapies meeting 2018. Ann Rheum Dis. 2019 Feb 02.

2. Taylor PC, Weinblatt ME, Burmester GR, Rooney TP, Witt S, Walls CD, Issa M, Salinas CA, Saifan C, Zhang X, Cardoso A, González-Gay MA, Takeuchi T. Cardiovascular Safety During Treatment with Baricitinib in Rheumatoid Arthritis. Arthritis Rheumatol. 2019 Jan 21.

3. Curtis JR, Flake DD, Weinblatt ME, Shadick NA, Østergaard M, Hetland ML, Brahe CH, Hwang YG, Furst DE, Strand V, Etzel CJ, Pappas DA, Wang X, Hwang CC, Sasso EH, Gutin A, Hitraya E, Lanchbury JS. Adjustment of the multi-biomarker disease activity score to account for age, sex and adiposity in patients with rheumatoid arthritis. Rheumatology (Oxford). 2018 Dec 24.

4. Desai RJ, Pawar A, Weinblatt ME, Kim SC. Comparative risk of venous thromboembolism with tofacitinib versus tumor necrosis factor inhibitors: A cohort study of rheumatoid arthritis patients. Arthritis Rheumatol. 2018 Dec 15.

5. Mease PJ, Genovese MC, Weinblatt ME, Peloso PM, Chen K, Othman AA, Li Y, Mansikka HT, Khatri A, Wishart N, Liu J. Phase II Study of ABT-122, a Tumor Necrosis Factor- and Interleukin-17A-Targeted Dual Variable Domain Immunoglobulin, in Patients With Psoriatic Arthritis With an Inadequate Response to Methotrexate. Arthritis Rheumatol. 2018 Nov; 70(11):1778-1789.

6. Genovese MC, Weinblatt ME, Mease PJ, Aelion JA, Peloso PM, Chen K, Li Y, Liu J, Othman AA, Khatri A, Mansikka HT, Leszczynski P. Dual inhibition of tumour necrosis factor and interleukin-17A with ABT-122: open-label long-term extension studies in rheumatoid arthritis or psoriatic arthritis. Rheumatology (Oxford). 2018 Nov 01; 57(11):1972-1981.

7. Fonseka CY, Rao DA, Teslovich NC, Korsunsky I, Hannes SK, Slowikowski K, Gurish MF, Donlin LT, Lederer JA, Weinblatt ME, Massarotti EM, Coblyn JS, Helfgott SM, Todd DJ, Bykerk VP, Karlson EW, Ermann J, Lee YC, Brenner MB, Raychaudhuri S. Mixed-effects association of single cells identifies an expanded effector CD4+ T cell subset in rheumatoid arthritis. Sci Transl Med. 2018 Oct 17; 10(463).

8. Genovese MC, Weinblatt ME, Aelion JA, Mansikka HT, Peloso PM, Chen K, Li Y, Othman AA, Khatri A, Khan NS, Padley RJ. ABT-122, a Bispecific Dual Variable Domain Immunoglobulin Targeting Tumor Necrosis Factor and Interleukin-17A, in Patients With Rheumatoid Arthritis With an Inadequate Response to Methotrexate: A Randomized, Double-Blind Study. Arthritis Rheumatol. 2018 Nov; 70(11):1710-1720.

9. Alemao E, Al MJ, Boonen AA, Stevenson MD, Verstappen SMM, Michaud K, Weinblatt ME, Rutten-van Mölken MPMH. Conceptual model for the health technology assessment of current and novel interventions in rheumatoid arthritis. PLoS One. 2018; 13(10):e0205013.

10. Shadick NA, Zibit MJ, Iannaccone CK, Thrower R, Sowell NF, Weinblatt ME, Solomon DH, Cui J. A Development and Feasibility Study of a Peer Support Telephone Program in Rheumatoid Arthritis. J Clin Rheumatol. 2018 Sep; 24(6):346-349.