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Myron Spector, PhD
Senior Scientist, Brigham and Women's Hospital
Member of the Faculty of the Harvard-MIT Health Sciences and Technology, Harvard Medical School

Brigham and Women's Hospital
Department of Orthopedic Surgery
75 Francis Street
Boston, MA 02115

Research Location: Medical Research Building

Research Email: mspector@rics.bwh.harvard.edu

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Research Narrative:

Myron Spector, Director of the Tissue Engineering Laboratories/Orthopaedic Research Laboratories has over 30 years of experience working in the biomaterials/tissue engineering field. He has directed his attention in recent years to the development of collagen-glycosaminoglycan sponge-like scaffolds and injectable biopolymer gels for musculoskeletal and nerve tissue engineering. He is the author of over 250 papers in peer-reviewed scientific journals, is Editor-in-Chielf of Biomedical Materials, and is a member of the Editorial Board of 8 journals.


Education:
Carnegie-Mellon University, 1971, Ph.D.
PhD

Honors/Awards:
2001 Elizabeth Winston-Lanier Kappa Delta Award from the American Academy of Orthopaedic Surgeons/Orthopaedic Research Society for the work entitled, “Expression of Muscle Actin in and Contraction of Chondrocytes, Osteoblasts, and Musculoskeletal Tissue Fibroblasts.”
2002 Clemson Award for Applied Biomaterials Research. Highest award in this category given by the Society for Biomaterials.
2004 John Charnley Award for 2004 from the Hip Society for the work entitled,
VA Research Career Scientist Award

Lab Members:
Hu-Ping Hsu, M.D., Supervisor, Surgical Research

Courses Taught:
Fall Terms, Harvard-MIT HST, Biomaterials-Tissue Interactions, 2.79J/3.96J/20.441J/HST.522J

Spring Terms, Haravrd-MIT HST, Cell-Matrix Mechanics, 2.785J/3.97J/20.411J/HST523J

Fall Terms, Harvard-MIT HST, Principles and Practice of Tissue Engineering, HST.535

Spring Terms, Harvard-MIT HST, Design of Medical Devices/Implants, 2.782J/3.961J/20.451J/HST.524J


Other Professional Activities:
1998-2001 Guest Professor of the Department of Materials Science and Engineering, Tsinghua University, China
1991-1997 Food and Drug Administration General and Plastic Surgery Devices Advisory Panel, (Chairman, 1993-1997)

Publications (Pulled from Harvard Catalyst Profiles):

1. Spector M. An interview with Joyce Y Wong: ensuring all voices in biomaterials community are heard. Biomed Mater. 2019 03 27; 14(3):030201.

2. Park J, Baranov P, Aydin A, Abdelgawad H, Singh D, Niu W, Kurisawa M, Spector M, Young MJ. In Situ Cross-linking Hydrogel as a Vehicle for Retinal Progenitor Cell Transplantation. Cell Transplant. 2019 Mar 27; 963689719825614.

3. Deng W, Shao F, He Q, Wang Q, Shi W, Yu Q, Cao X, Feng C, Bi S, Chen J, Ma P, Li Y, Gong A, Tong S, Yu J, Spector M, Xu X, Zhang Z. EMSCs Build an All-in-One Niche via Cell-Cell Lipid Raft Assembly for Promoted Neuronal but Suppressed Astroglial Differentiation of Neural Stem Cells. Adv Mater. 2019 Mar; 31(10):e1806861.

4. Cao X, Wang J, Deng W, Chen J, Wang Y, Zhou J, Du P, Xu W, Wang Q, Wang Q, Yu Q, Spector M, Yu J, Xu X. Photoluminescent Cationic Carbon Dots as efficient Non-Viral Delivery of Plasmid SOX9 and Chondrogenesis of Fibroblasts. Sci Rep. 2018 May 04; 8(1):7057.

5. Spector M. Biomedical materials to meet the challenges of the aging epidemic. Biomed Mater. 2018 03 16; 13(3):030201.

6. Ambra LF, de Girolamo L, Niu W, Phan A, Spector M, Gomoll AH. No effect of topical application of tranexamic acid on articular cartilage. Knee Surg Sports Traumatol Arthrosc. 2019 Mar; 27(3):931-935.

7. Egawa N, Shindo A, Liang AC, Du Y, Xing C, Lo EK, Itoh K, Kinoshita H, Maki T, Takahashi R, Sudo R, Spector M, Lok J, Arai K. A Novel Three-Dimensional Culture System for Oligodendrocyte Precursor Cells. Stem Cells Dev. 2017 07 15; 26(14):1078-1085.

8. Chan SJ, Love C, Spector M, Cool SM, Nurcombe V, Lo EH. Endogenous regeneration: Engineering growth factors for stroke. Neurochem Int. 2017 Jul; 107:57-65.

9. Foldager CB, Bendtsen M, Berg LC, Brinchmann JE, Brittberg M, Bunger C, Canseco J, Chen L, Christensen BB, Colombier P, Deleuran BW, Edwards J, Elmengaard B, Farr J, Gatenholm B, Gomoll AH, Hui JH, Jakobsen RB, Joergensen NL, Kassem M, Koch T, Kold S, Krogsgaard MR, Lauridsen H, Le D, Le Visage C, Lind M, Nygaard JV, Olesen ML, Pedersen M, Rathcke M, Richardson JB, Roberts S, Rölfing JH, Sakai D, Toh WS, Urban J, Spector M. Aarhus Regenerative Orthopaedics Symposium (AROS). Acta Orthop. 2016 Dec; 87(sup363):1-5.

10. Zhang Z, Li Z, Deng W, He Q, Wang Q, Shi W, Chen Q, Yang W, Spector M, Gong A, Yu J, Xu X. Ectoderm mesenchymal stem cells promote differentiation and maturation of oligodendrocyte precursor cells. Biochem Biophys Res Commun. 2016 11 25; 480(4):727-733.