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Michael O'Leary, MD
Senior Surgeon, Brigham and Women's Hospital
Professor of Surgery, Harvard Medical School

Brigham and Women's Hospital
Department of Surgery
75 Francis Street
Boston, MA 02115

Research Narrative:

My major focus has been on the development and validation of hard measures of subjective outcomes in Urologic disease. This has resulted in six indices that are now widely used throughout the world, having been linguistically and culturally validated in over a dozen languages. These include:

  • The International Prostate Symptom Score (Journal of Urology 153 Volume 1:99-103,1995)
  • The Symptom Problem Index (Urology 49 Suppl 5A: 58-63,1997, the BPH Impact Index (MedCare 33 Volume 4:1450155,1995)
  • Brief Male Sexual Function Inventory (Urology 46 Volume 5:697-706,1995)
  • The National Institutes of Health Chronic Prostatitis Symptom Index (Journal of Urology 162(8): 369-375, 1999)
  • The Interstitial Cystitis Symptom and Problem Indices (Urology 49: Suppl 5A:58-63,1997), both of which have been funded by NIH R0-1 Grants.

I have also been an investigator in clinical trials for new modalities of therapy for erectile dysfunction, some of which are now standard treatment (NEJM 334 Volume 14: 873-877,1996).

My current research focus includes benign prostatic hyperplasia (BPH), interstitial cystitis (IC), chronic prostatitis, and prostate cancer.

University of California, San Francisco, School of Medicine/Stanford University School of Medicine, 1989, Fellowship
Massachusetts General Hospital, 1987, Urology Residency
New England Medical Center - Tufts School of Medicine, 1982, Urology Residency
George Washington University School of Medicine and Health Sciences, 1980, MD

Other Professional Activities:
Director of Men's Health Center, Brigham and Women's Hospital

Publications (Pulled from Harvard Catalyst Profiles):

1. Whealon MD, Gahagan JV, Sujatha-Baskar S, O'Leary MP, Selleck M, Dumitra S, Lee B, Senthil M, Pigazzi A. Is Fecal Diversion Needed in Pelvic Anastomoses During Hyperthermic Intraperitoneal Chemotherapy (HIPEC)? Ann Surg Oncol. 2017 Apr 14.

2. Barry MJ, Fowler FJ, O'leary MP, Bruskewitz RC, Holtgrewe HL, Mebust WK, Cockett AT. The American Urological Association Symptom Index for Benign Prostatic Hyperplasia. J Urol. 2017 Feb; 197(2S):S189-S197.

3. O'Leary MP, Ashman ZW, Plurad DS, Kim DY. Urachal Cyst Causing Small Bowel Obstruction in an Adult with a Virgin Abdomen. Case Rep Surg. 2016; 2016:3247087.

4. Choi AH, O'Leary MP, Merchant SJ, Sun V, Chao J, Raz DJ, Kim JY, Kim J. Complications of Feeding Jejunostomy Tubes in Patients with Gastroesophageal Cancer. J Gastrointest Surg. 2017 Feb; 21(2):259-265.

5. O'Leary MP, Neville AL, Keeley JA, Kim DY, de Virgilio C, Plurad DS. Predictors of Ischemic Bowel in Patients with Small Bowel Obstruction. Am Surg. 2016 Oct; 82(10):992-994.

6. O'Leary MP, Parrish AB, Tom CM, MacLaughlin BW, Petrie BA. Staging Rectal Cancer: The Utility of Chest Radiograph and Chest Computed Tomography. Am Surg. 2016 Oct; 82(10):1005-1008.

7. O'Leary MP, Keeley JA, Yule A, Suruki C, Plurad DS, Moazzez A, Neville AL, Putnam BA, Kim DY. Clinical predictors of early acute respiratory distress syndrome in trauma patients. Am J Surg. 2016 Dec; 212(6):1096-1100.

8. Basaria S, Jasuja R, Huang G, Wharton W, Pan H, Pencina K, Li Z, Travison TG, Bhawan J, Gonthier R, Labrie F, Dury AY, Serra C, Papazian A, O'Leary M, Amr S, Storer TW, Stern E, Bhasin S. Characteristics of Men Who Report Persistent Sexual Symptoms After Finasteride Use for Hair Loss. J Clin Endocrinol Metab. 2016 Dec; 101(12):4669-4680.

9. Warner SG, Haddad D, Au J, Carson JS, O'Leary MP, Lewis C, Monette S, Fong Y. Oncolytic herpes simplex virus kills stem-like tumor-initiating colon cancer cells. Mol Ther Oncolytics. 2016; 3:16013.

10. Chao GF, Krishna N, Aizer AA, Dalela D, Hanske J, Li H, Meyer CP, Kim SP, Mahal BA, Reznor G, Schmid M, Choueiri TK, Nguyen PL, O'Leary M, Trinh QD. Asian Americans and prostate cancer: A nationwide population-based analysis. Urol Oncol. 2016 May; 34(5):233.e7-15.