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Daniel Hal Solomon, MD, MPH
Associate Physician, Brigham and Women's Hospital
Professor of Medicine, Harvard Medical School

Brigham and Women's Hospital
Department of Medicine
Rheumatology, Immunology
75 Francis Street
Boston, MA 02115

Research Email:

Research Narrative:
            Dr. Solomon is a population scientist focusing on the epidemiology and health services of rheumatic disease. He serves as the Chief of the Section of Clinical Sciences in the Division of Rheumatology at BWH. His research work is primarily funded by the NIH, AHRQ, and foundations. He has served major roles at the American College of Rheumatology and within the osteoporosis community as well. 
His achievements in population science research focuses on three areas. First, he has been a leading investigator on the cardiovascular safety of nonsteroidal anti-inflammatory drugs (NSAIDs). He has been the first author on 12 original articles in this area, has several industry-sponsored grants and one AHRQ sponsored grant in this area, and led the American College of Rheumatology Blue Ribbon Panel to set recommendations for NSAIDs. He has given over 15 invited talks on this topic and currently serve on the Executive Committee of the largest randomized controlled trial on the cardiovascular safety of NSAIDs and selective COX-2 inhibitors.
 Second, he has focused much of his research on cardiovascular manifestations of rheumatoid arthritis and its treatment. He completed one NIH grant on this topic and have another current NIH grant to study insulin and glucose metabolism in rheumatoid arthritis. He is the first author on 5 publications describing the epidemiology of cardiovascular disease in patients with rheumatoid arthritis and has given 8 invited lectures in this area.
Finally, he has helped define standards for osteoporosis care improvement. He has received two NIH grants in this area. A current NIH funded study is a large-scale adherence improvement trial for osteoporosis medications. He has first authored 8 original articles in this area and given 10 invited lectures on osteoporosis improvement. He serves on the steering committee of the National Action Plan for Bone Health, focusing on methods to improve dissemination of proven improvement methods, as well as on the American Orthopaedic Association’s Own the Bone Program.
               He teaches and mentors primarily in rheumatic disease epidemiology and pharmacoepidemiology.   He has mentored over 25 fellows and trainees and have a K24 award from NIH with 25% effort devoted to research training and mentoring. He developed and directed a course in clinical research for rheumatologists. As well, he teaches residents in the BWH Department of Medicine’s lecture series and journal club.

Investigative Interests:  drug safety and effectiveness

Harvard School of Public Health, 1998, MPH
Yale School of Medicine, 1992, MD

American College of Rheumatology Young Investigator Award
NIH Mentoring Award
Chief, Section of Clinical Sciences, Rheumatology
Co-Director, Patient-Centered Research Center

Publications (Pulled from Harvard Catalyst Profiles):

1. Yoshida K, Hernández-Díaz S, Solomon DH, Jackson JW, Gagne JJ, Glynn RJ, Franklin JM. Matching Weights to Simultaneously Compare Three Treatment Groups: Comparison to Three-way Matching. Epidemiology. 2017 May; 28(3):387-395.

2. Solomon DH, Shadick NA, Weinblatt ME, Frits M, Iannaccone C, Zak A, Korzenik JR. Clinical patient registry recruitment and retention: a survey of patients in two chronic disease registries. BMC Med Res Methodol. 2017 Apr 17; 17(1):59.

3. Radner H, Yoshida K, Tedeschi S, Studenic P, Frits M, Iannaccone C, Shadick NA, Weinblatt M, Aletaha D, Smolen JS, Solomon DH. Different Rating of Global Rheumatoid Arthritis Disease Activity in Rheumatoid Arthritis Patients With Multiple Morbidities. Arthritis Rheumatol. 2017 Apr; 69(4):720-727.

4. Lin TC, Hashemi N, Kim SC, Kao Yang YH, Yoshida K, Tedeschi S, Desai R, Solomon DH. The practice pattern of hepatitis b testing in rheumatoid arthritis patients: A cross-national comparison between US and Taiwan. Arthritis Care Res (Hoboken). 2017 Mar 20.

5. Franklin JM, Schneeweiss S, Solomon DH. Assessment of Confounders in Comparative Effectiveness Studies From Secondary Databases. Am J Epidemiol. 2017 Mar 15; 185(6):474-478.

6. Desai RJ, Solomon DH. Use of large healthcare databases for rheumatology clinical research. Curr Opin Rheumatol. 2017 Mar; 29(2):138-143.

7. Kim SC, Solomon DH, Rogers JR, Gale S, Klearman M, Sarsour K, Schneeweiss S. Cardiovascular Safety of Tocilizumab Versus Tumor Necrosis Factor Inhibitors in Patients With Rheumatoid Arthritis: A Multi-Database Cohort Study. Arthritis Rheumatol. 2017 Feb 28.

8. Jackson EA, Ruppert K, Derby CA, Lian Y, Neal-Perry G, Habel LA, Tepper PG, Harlow SD, Solomon DH. Effect of Race and Ethnicity on Antihypertensive Medication Utilization Among Women in the United States: Study of Women's Health Across the Nation (SWAN). J Am Heart Assoc. 2017 Feb 23; 6(3).

9. Tedeschi SK, Frits M, Cui J, Zhang ZZ, Mahmoud T, Iannaccone C, Lin TC, Yoshida K, Weinblatt ME, Shadick NA, Solomon DH. Diet and Rheumatoid Arthritis Symptoms: Survey Results From a Rheumatoid Arthritis Registry. Arthritis Care Res (Hoboken). 2017 Feb 19.

10. Sparks JA, Barbhaiya M, Karlson EW, Ritter SY, Raychaudhuri S, Corrigan CC, Lu F, Selhub J, Chasman DI, Paynter NP, Ridker PM, Solomon DH. Investigating methotrexate toxicity within a randomized double-blinded, placebo-controlled trial: Rationale and design of the Cardiovascular Inflammation Reduction Trial-Adverse Events (CIRT-AE) Study. Semin Arthritis Rheum. 2017 Feb 10.