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Edwin Kepner Silverman, MD, PhD
Physician, Brigham and Women's Hospital
Professor of Medicine, Harvard Medical School

Brigham and Women's Hospital
Department of Medicine
Channing Division of Network Medicine
75 Francis Street
Boston, MA 02115

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Research Narrative:

I am a pulmonologist and genetic epidemiologist. I am the Chief of the Channing Division of Network Medicine at Brigham and Women’s Hospital, where we are using network science approaches to analyze genetic, Omics, and phenotypic data in complex diseases. I am the Principal Investigator of multiple studies of COPD genetics, including an extended pedigree study of severe, early-onset COPD (Boston Early-Onset COPD Study); I am also one of two national Principal Investigators for the COPDGene Study. My recent work has focused on identifying functional genetic variants influencing COPD susceptibility; integrating imaging, physiology, clinical characterization, and genetics to identify COPD subtypes; and defining networks of interacting biological factors in COPD pathogenesis. I am the co-director of the Channing T32 training program, and I have mentored 33 post-doctoral fellows.

Washington University School of Medicine, 1990, MD-PhD