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Luc Djoussé, MD, MPH, DSc
Associate Epidemiologist, Brigham and Women's Hospital
Associate Professor of Medicine, Harvard Medical School

Brigham and Women's Hospital
Department of Medicine
Division of Aging
75 Francis Street
Boston, MA 02115


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Research Narrative:

Since joining the Division of Aging in 2005, Dr. Djoussé's national and international reputation has continued to grow. His research is focused on nutrition and genetic factors, and the interaction between both on the risk of cardiovascular disease. Over the past decade, Dr. Djoussé's work has contributed to our understanding of the role that diet and other modifiable factors play on the risk of hypertension, coronary heart disease, stroke, diabetes, and heart failure, primarily using major epidemiologic cohorts such as the Framingham Heart Study, the NHLBI Family Heart Study, the HyperGen Study, the Physicians' Health Study, the Cardiovascular Health Study, and the Women's Health Study. His work has also advanced our knowledge of the burgeoning field of gene-environment interactions, particularly as they relate to the intake of moderate alcohol consumption and cardiovascular disease. His recent work has demonstrated beneficial effects of a healthy diet and moderate alcohol consumption on the risk of hypertension, heart failure, and diabetes.

Dr. Djoussé is a fellow of the American Heart Association.


Education:
Boston University , 2002, DSc
Boston University , 1996, MPH
University of Saarland, Germany , 1993, MD

Publications (Pulled from Harvard Catalyst Profiles):

1. Lai H, Imamura F, Korat AA, Murphy R, Tintle N, Bassett J, Chen J, Kröger J, Forouhi N, Schulze M, Harris W, Ramachandran V, Hu F, Giles G, Djousse L, Brouwer I, Wu J, Marklund M, Micha R, Lemaitre R, McKnight B, Siscovick D, Shadyab A, Manson J, Howard B, Robinson J, Wallace R, Mozaffarian D. Trans Fatty Acid Biomarkers and Incident Type 2 Diabetes: Pooled Analysis from 10 Prospective Cohort Studies in the Fatty Acids and Outcome Research Consortium (FORCE) (OR33-02-19). Curr Dev Nutr. 2019 Jun; 3(Suppl 1).

2. Honerlaw JP, Ho YL, Nguyen XT, Cho K, Vassy JL, Gagnon DR, O'Donnell CJ, Gaziano JM, Wilson PWF, Djousse L. Fried food consumption and risk of coronary artery disease: The Million Veteran Program. Clin Nutr. 2019 Jun 05.

3. Garg PK, Biggs ML, Barzilay J, Djousse L, Hirsch C, Ix JH, Kizer JR, Tracy RP, Newman AB, Siscovick DS, Mukamal KJ. Advanced glycation end product carboxymethyl-lysine and risk of incident peripheral artery disease in older adults: The Cardiovascular Health Study. Diab Vasc Dis Res. 2019 May 08; 1479164119847481.

4. Imran TF, Kurgansky KE, Patel YR, Orkaby AR, McLean RR, Ho YL, Cho K, Gaziano JM, Djousse L, Gagnon DR, Joseph J. Serial sodium values and adverse outcomes in heart failure with preserved ejection fraction. Int J Cardiol. 2019 Sep 01; 290:119-124.

5. Benjamin EJ, Muntner P, Alonso A, Bittencourt MS, Callaway CW, Carson AP, Chamberlain AM, Chang AR, Cheng S, Das SR, Delling FN, Djousse L, Elkind MSV, Ferguson JF, Fornage M, Jordan LC, Khan SS, Kissela BM, Knutson KL, Kwan TW, Lackland DT, Lewis TT, Lichtman JH, Longenecker CT, Loop MS, Lutsey PL, Martin SS, Matsushita K, Moran AE, Mussolino ME, O'Flaherty M, Pandey A, Perak AM, Rosamond WD, Roth GA, Sampson UKA, Satou GM, Schroeder EB, Shah SH, Spartano NL, Stokes A, Tirschwell DL, Tsao CW, Turakhia MP, VanWagner LB, Wilkins JT, Wong SS, Virani SS. Heart Disease and Stroke Statistics-2019 Update: A Report From the American Heart Association. Circulation. 2019 03 05; 139(10):e56-e528.

6. Shantakumar S, Nordstrom BL, Hall SA, Djousse L, van Herk-Sukel MPP, Fraeman KH, Gagnon DR, Chagin K, Nelson JJ. Prescriber Compliance With Liver Monitoring Guidelines for Pazopanib in the Postapproval Setting: Results From a Distributed Research Network. J Patient Saf. 2019 Mar; 15(1):55-60.

7. Imran TF, Posner D, Honerlaw J, Vassy JL, Song RJ, Ho YL, Kittner SJ, Liao KP, Cai T, O'Donnell CJ, Djousse L, Gagnon DR, Gaziano JM, Wilson PW, Cho K. A phenotyping algorithm to identify acute ischemic stroke accurately from a national biobank: the Million Veteran Program. Clin Epidemiol. 2018; 10:1509-1521.

8. Orkaby AR, Nussbaum L, Ho YL, Gagnon D, Quach L, Ward R, Quaden R, Yaksic E, Harrington K, Paik JM, Kim DH, Wilson PW, Gaziano MJ, Djousse L, Cho K, Driver JA. The Burden of Frailty Among U.S. Veterans and Its Association With Mortality, 2002-2012. J Gerontol A Biol Sci Med Sci. 2018 Oct 11.

9. Massera D, Biggs ML, Walker MD, Mukamal KJ, Ix JH, Djousse L, Valderrábano RJ, Siscovick DS, Tracy RP, Xue X, Kizer JR. Biochemical Markers of Bone Turnover and Risk of Incident Diabetes in Older Women: The Cardiovascular Health Study. Diabetes Care. 2018 09; 41(9):1901-1908.

10. Patel YR, Robbins JM, Kurgansky KE, Imran T, Orkaby AR, McLean RR, Ho YL, Cho K, Michael Gaziano J, Djousse L, Gagnon DR, Joseph J. Development and validation of a heart failure with preserved ejection fraction cohort using electronic medical records. BMC Cardiovasc Disord. 2018 06 28; 18(1):128.