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Elliot Israel, MD
Physician, Brigham and Women's Hospital
Professor of Medicine, Harvard Medical School

Brigham and Women's Hospital
Department of Medicine
Pulmonary
75 Francis Street
Boston, MA 02115


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Research Narrative:

Dr. Elliot Israel is Professor of Medicine at Harvard Medical School in Boston, Massachusetts. He is Director of Clinical Research in the Pulmonary Division. He was honored with the Daniel D. Federman Outstanding Clinical Educator Award by Harvard Medical School.  Dr. Israel’s major research interests include mediators of airway reactivity, biomarkers of asthma, therapeutic interventions to improve asthma outcomes, pharmacogenomics, and approaches to understanding and minimizing disparities in asthma morbidity. He has several grants from the National Institutes of Health to study asthma, severe asthma,  and leads one of 8 sites throughout the country supported by the NIH to conduct research into better asthma treatments. He is interested in disparities in asthma outcomes among minority and disadvantaged populations. He has conducted, and is conducting, studies in African Americans with asthma. These studies have involved investigating genetic determinants of differentiated responses to medications and the effectiveness of individualized therapeutic approaches in this population.  He was named one of Boston’s best in Pulmonary Medicine by Boston Magazine. He has authored or coauthored more than 125 articles, reviews, and abstracts in such journals as the New England Journal of Medicine, JAMA, American Journal of Respiratory and Critical Care Medicine, Journal of Allergy and Clinical Immunology, and The Lancet. Dr. Israel received his medical degree and completed his internship at Johns Hopkins University School of Medicine in Baltimore, Maryland. After completing his residency at New York Hospital/Cornell Medical College in New York City, he obtained clinical and research fellowships in both Pulmonary and Critical Care Medicine and Allergy and Immunology from Brigham and Women’s Hospital and Harvard Medical School in Boston.


Education:
Johns Hopkins University School of Medicine, 1979, MD

Publications (Pulled from Harvard Catalyst Profiles):

1. Cardet JC, Jiang X, Lu Q, Gerard N, McIntire K, Boushey HA, Castro M, Chinchilli VM, Codispoti CD, Dyer AM, Holguin F, Kraft M, Lazarus S, Lemanske RF, Lugogo N, Mauger D, Moore WC, Moy J, Ortega VE, Peters SP, Smith LJ, Solway J, Sorkness CA, Sumino K, Wechsler ME, Wenzel S, Israel E. Loss of bronchoprotection with ICS+LABA, beta-receptor dynamics, and the effect of alendronate. J Allergy Clin Immunol. 2019 Mar 11.

2. Ramadan AA, Gaffin JM, Israel E, Phipatanakul W. Asthma and Corticosteroid Responses in Childhood and Adult Asthma. Clin Chest Med. 2019 Mar; 40(1):163-177.

3. Kankaanranta H, Israel E. What Patients Can Tell Us About Their Asthma. J Allergy Clin Immunol Pract. 2019 Mar; 7(3):906-907.

4. Wu W, Bang S, Bleecker ER, Castro M, Denlinger L, Erzurum SC, Fahy JV, Fitzpatrick AM, Gaston BM, Hastie AT, Israel E, Jarjour NN, Levy BD, Mauger DT, Meyers DA, Moore WC, Peters M, Phillips BR, Phipatanakul W, Sorkness RL, Wenzel SE. Multiview Cluster Analysis Identifies Variable Corticosteroid Response Phenotypes in Severe Asthma. Am J Respir Crit Care Med. 2019 Jan 25.

5. Guilbert TW, Bacharier LB, Mauger DT, Phipatanakul W, Szefler SJ, Boehmer S, Beigelman A, Fitzpatrick AM, Jackson DJ, Baxi SN, Benson M, Burnham CD, Cabana MD, Castro M, Chmiel JF, Covar R, Daines M, Gaffin JM, Gentile DA, Holguin F, Israel E, Kelly HW, Lazarus SC, Lemanske RF, Ly N, Meade K, Morgan W, Moy J, Olin JT, Peters SP, Pongracic JA, Raissy HH, Ross K, Sheehan WJ, Sorkness C, Teague WG, Thyne S, Martinez FD. Challenges in assessing the efficacy of systemic corticosteroids for severe wheezing episodes in preschool children. J Allergy Clin Immunol. 2019 Jan 17.

6. Fitzpatrick AM, Gillespie SE, Mauger DT, Phillips BR, Bleecker ER, Israel E, Meyers DA, Moore WC, Sorkness RL, Wenzel SE, Bacharier LB, Castro M, Denlinger LC, Erzurum SC, Fahy JV, Gaston BM, Jarjour NN, Larkin A, Levy BD, Ly NP, Ortega VE, Peters SP, Phipatanakul W, Ramratnam S, Teague WG. Racial disparities in asthma-related health care use in the National Heart, Lung, and Blood Institute's Severe Asthma Research Program. J Allergy Clin Immunol. 2019 Jan 08.

7. Sorkness CA, King TS, Dyer AM, Chinchilli VM, Mauger DT, Krishnan JA, Blake K, Castro M, Covar R, Israel E, Kraft M, Lang JE, Lugogo N, Peters SP, Wechsler ME, Wenzel SE, Lazarus SC. Adapting clinical trial design to maintain meaningful outcomes during a multicenter asthma trial in the precision medicine era. Contemp Clin Trials. 2019 Feb; 77:98-103.

8. Yawn BP, Israel E, Wechsler ME, Pace W, Madison S, Manning B, Doros G, Fuhlbrigge A. The asthma Symptom Free Days Questionnaire: how reliable are patient responses? J Asthma. 2018 Oct 26; 1-9.

9. Cahill KN, Murphy K, Singer J, Israel E, Boyce JA, Laidlaw TM. Plasma tryptase elevation during aspirin-induced reactions in aspirin-exacerbated respiratory disease. J Allergy Clin Immunol. 2019 Feb; 143(2):799-803.e2.

10. Cardet JC, Codispoti CD, King TS, Bacharier L, Carr T, Castro M, Chinchilli V, Dunn R, Holquing F, Engle L, Nelson K, Ortega VE, Peters M, Ramratnam S, Krishnan JA, Wechsler ME, Israel E. Predictors of inhaled corticosteroid taper failure in adults with asthma. J Allergy Clin Immunol Pract. 2018 Sep 19.