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Francine Grodstein, SCD
Epidemiologist, Brigham and Women's Hospital
Professor of Medicine, Harvard Medical School

Brigham and Women's Hospital
Department of Medicine
Channing Division of Network Medicine
75 Francis Street
Boston, MA 02115

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Research Narrative:
Dr. Grodstein’s research focuses on healthy aging, particularly in women. Her primary research base is the Nurses’ Health Study (NHS), where she leads a study of cognitive function among the oldest participants. This includes several repeated measures of function in 20,000 women aged 70 years and over. In addition, she leads cognitive substudies within three large-scale randomized clinical trials of vitamin supplements and aspirin with a total of 16,000 participants in the cognitive cohort. 
She also is Scientific Director of the Nurses' Health Studies (NHS) overall. The NHS includes over 200,000 women who have been followed for 30+ years, with biennial questionnaires on lifestyle and health, as 
2 well as a biorepository with blood and urine samples from 60,000 of the participants and tumor tissue in 20,000 of the women who developed cancers. The NHS represents a rich source of research for the entire BWH community. 



Harvard School of Public Health , 1992, SCD

Publications (Pulled from Harvard Catalyst Profiles):

1. Erekson E, Hagan KA, Austin A, Donald Carmichael MD, Minassian VA, Grodstein F, Bynum JP. Outpatient Evaluation and Management Visits for Urinary Incontinence in Older Women. J Urol. 2019 Mar 13; 101097JU0000000000000223.

2. Kim ES, James P, Zevon ES, Trudel-Fitzgerald C, Kubzansky LD, Grodstein F. Optimism and Healthy Aging in Women and Men. Am J Epidemiol. 2019 Mar 05.

3. Kim DH, Afilalo J, Shi SM, Popma JJ, Khabbaz KR, Laham RJ, Grodstein F, Guibone K, Lux E, Lipsitz LA. Evaluation of Changes in Functional Status in the Year After Aortic Valve Replacement. JAMA Intern Med. 2019 Feb 04.

4. Devore E, Hall KE, Schernhammer ES, Grodstein F. CE: Original Research: Midlife Hypertension and Hypercholesterolemia in Relation to Cognitive Function Later in Life in Black Women. Am J Nurs. 2019 Feb; 119(2):22-30.

5. Curhan SG, Willett WC, Grodstein F, Curhan GC. Longitudinal study of hearing loss and subjective cognitive function decline in men. Alzheimers Dement. 2019 Jan 21.

6. Austin AM, Kapadia NS, Brooks GA, Onega TL, Eliassen AH, Tamimi RM, Holmes M, Wang Q, Grodstein F, Tosteson ANA. Comparison of treatment of early-stage breast cancer among Nurses' Health Study participants and other Medicare beneficiaries. Breast Cancer Res Treat. 2019 Jan 03.

7. James P, Kim ES, Kubzansky LD, Zevon ES, Trudel-Fitzgerald C, Grodstein F. Optimism and Healthy Aging in Women. Am J Prev Med. 2019 Jan; 56(1):116-124.

8. Bhupathiraju SN, Grodstein F, Stampfer MJ, Willett WC, Crandall CJ, Shifren JL, Manson JE. Vaginal estrogen use and chronic disease risk in the Nurses' Health Study. Menopause. 2018 Dec 17.

9. Kang JH, Bynum JPW, Zhang L, Grodstein F, Stevenson DG. Predictors of Advance Care Planning in Older Women: The Nurses' Health Study. J Am Geriatr Soc. 2019 Feb; 67(2):292-301.

10. Bronson MR, Kapadia NS, Austin AM, Wang Q, Feskanich D, Bynum JPW, Grodstein F, Tosteson ANA. Leveraging Linkage of Cohort Studies With Administrative Claims Data to Identify Individuals With Cancer. Med Care. 2018 Dec; 56(12):e83-e89.